Residual effects of low dose of suvorexant, zolpidem, and ramelteon in healthy elderly subjects: A randomized double-blind study.

Author: HanGoEun, ImanishiAya, KanbayashiTakashi, NishinoSeiji, ParkInsung, SatakeMasahiro, ShioyaTakanobu, TeruiYoshino, UemuraSachiko Ito

Paper Details 
Original Abstract of the Article :
Current hypnotic agents have next-day residual effects. The new orexin antagonist, suvorexant, has little muscle relaxation effect on the physical and cognitive function in the following morning and daytime. In this study, the effects of suvorexant, zolpidem, ramelteon and placebo in elderly subject...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515713/

データ提供:米国国立医学図書館(NLM)

Investigating Residual Effects of Hypnotic Medications in Elderly Subjects

Sleep is a vital part of our lives, allowing us to recharge and restore our bodies and minds. This study examines the residual effects of commonly used hypnotic medications in elderly individuals, specifically focusing on the new orexin antagonist, suvorexant, compared to zolpidem and ramelteon. Imagine a desert night where the stars guide travelers through the darkness. This study explores the impact of different medications on sleep and their lingering effects the following morning. The researchers conducted a randomized, double-blind study, like a carefully planned caravan journey, to assess the effects of these medications on elderly participants. Their analysis revealed that while zolpidem and ramelteon produced noticeable residual effects the next day, suvorexant showed minimal impact on physical and cognitive function, suggesting a potential advantage for those seeking a more restorative sleep experience.

A Clearer Dawn: Suvorexant Shows Promise for Restorative Sleep

This study offers hope for elderly individuals seeking a medication that promotes a restful night's sleep without lingering daytime effects. The researchers, like experienced desert guides, meticulously compared the effects of suvorexant, zolpidem, and ramelteon. Their findings, like a refreshing oasis in the desert of sleep disturbances, revealed that suvorexant had a significantly lower impact on physical and cognitive function the following day.

Finding the Right Path: Tailoring Sleep Medications for Individual Needs

This study highlights the importance of individualizing sleep medication choices. The researchers' meticulous comparison of different medications, like a careful assessment of different desert routes, demonstrated that suvorexant might be a better option for elderly individuals who want to wake up feeling refreshed and ready for the day. This study underscores the importance of consulting with healthcare professionals to determine the best course of action for individual sleep needs.

Dr.Camel's Conclusion

This study provides valuable insights into the residual effects of hypnotic medications in elderly subjects, suggesting that suvorexant may be a promising option for individuals seeking a more restorative sleep experience without lingering daytime drowsiness.

Date :
  1. Date Completed 2022-09-29
  2. Date Revised 2022-11-04
Further Info :

Pubmed ID

35748642

DOI: Digital Object Identifier

PMC9515713

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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