Suspected cholinergic toxicity due to cevimeline hydrochloride and Bacopa monnieri interaction: a case report.

Author: AcquaruloBlake, MacicaCarolyn M, TandonPriya

Paper Details 
Original Abstract of the Article :
Muscarinic agonists are indicated for the treatment of many conditions including ileus, urinary retention, glaucoma, and Sjögren's syndrome. Due to their lack of tissue specificity, these drugs can lead to undesirable side effects at off-target sites and may be potentiated by supplements that impact...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241182/

データ提供:米国国立医学図書館(NLM)

Cevimeline Hydrochloride and Bacopa Monnieri: A Case of Potential Interaction in the Desert of Pharmacology

The intricate world of pharmacology, like a vast desert with hidden pathways and potential pitfalls, can sometimes lead to unexpected interactions between medications and supplements. This case report explores a suspected cholinergic toxicity due to a potential interaction between cevimeline hydrochloride, a muscarinic agonist, and Bacopa monnieri, a popular herbal supplement. The researchers, like desert explorers uncovering a forgotten inscription, analyzed the case to understand the potential mechanisms behind this adverse event.

Cholinergic Toxicity: A Warning Sign in the Desert of Medication Interactions

The case report, like a desert warning sign highlighting a dangerous path, highlights the potential risks associated with drug interactions, especially when combining medications with herbal supplements. The case suggests that Bacopa monnieri, by potentially affecting the half-life of cevimeline hydrochloride, may have contributed to an increased risk of cholinergic toxicity. This underscores the importance of being aware of potential interactions between medications and supplements, especially for individuals taking drugs with a narrow therapeutic window.

Navigating the Desert of Medication: Caution and Collaboration

For individuals taking medications, especially those with a narrow therapeutic window, this case report serves as a reminder to be cautious about potential interactions with herbal supplements. It's crucial to consult with a healthcare professional to discuss potential interactions and ensure safe and effective medication use. The desert of medication can be a complex and sometimes unpredictable landscape, requiring careful navigation and collaboration between patients and healthcare professionals to ensure safety and well-being.

Dr. Camel's Conclusion

This case report, like a well-placed oasis in the vast desert of pharmacology, serves as a reminder of the potential risks associated with drug interactions. The case highlights the importance of transparency and communication between patients and healthcare professionals to minimize the risks of adverse events. The desert of medication can be a complex and sometimes treacherous journey, requiring careful consideration of potential interactions and a commitment to collaborative care.
Date :
  1. Date Completed 2022-06-30
  2. Date Revised 2022-07-16
Further Info :

Pubmed ID

35765109

DOI: Digital Object Identifier

PMC9241182

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.