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Ciprofloxacin-loaded dissolving polymeric microneedles as a potential therapeutic for the treatment of <i>S. aureus</i> skin infections.

Author: AbdelghanySharif, Al FawaresMaram, Al ThaherYazan, Al-BakriAmal G, AlshaerWalhan, MansourRanda Sh, ZuriekatSaja

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study explored the use of microneedles as a potential delivery system for the antibiotic ciprofloxacin (CIP) to treat skin infections like cellulitis. The study found that the microneedle formulation of CIP delivered the drug more effectively into deeper skin layers, where it could better fight the bacteria causing the infection.
Paper Details　
Original Abstract of the Article :
Microneedles have been widely studied for many topical and transdermal therapeutics due to their ability to painlessly puncture the skin, thereby bypassing the stratum corneum, the main skin barrier. In this study, ciprofloxacin (CIP) was loaded into dissolving polymeric microneedles prepared by a t...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235833/

データ提供：米国国立医学図書館（NLM）

Ciprofloxacin Microneedles: A New Weapon in the Fight Against Skin Infections

The desert of skin infections is a challenging one, with bacteria constantly seeking to penetrate our defenses. This study investigates the potential of ciprofloxacin-loaded dissolving polymeric microneedles as a novel therapeutic approach for treating *Staphylococcus aureus* skin infections. The authors explore the advantages of this technology, highlighting its potential to improve drug delivery and enhance efficacy.

Microneedles: A New Oasis in the Desert of Skin Infections

The study demonstrates the effectiveness of ciprofloxacin-loaded microneedles in delivering the drug to deeper skin layers, where it can effectively target bacteria. The authors find that this approach significantly enhances the antimicrobial activity of ciprofloxacin compared to traditional topical formulations. It's like using a cleverly designed water-gathering system to reach the heart of a desert oasis – microneedles effectively target the source of infection.

A Promising Future

This research highlights the potential of microneedle technology to improve the treatment of skin infections. The authors suggest that this approach could lead to more effective and convenient therapies, offering a beacon of hope in the desert of antimicrobial resistance. It's like discovering a new and innovative well in the desert – this technology offers a valuable resource for addressing a critical healthcare challenge.

Dr.Camel's Conclusion

This study offers a promising glimpse into the future of skin infection treatment. It's a reminder that even in the seemingly desolate desert of antimicrobial resistance, we can find innovative solutions through creative research and development.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-09-16
Further Info :

Pubmed ID

35812251

DOI: Digital Object Identifier

PMC9235833

Related Literature

Article Analysis
・Effective treatment of skin infections
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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