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Ditans: a new prospective for the therapy of migraine attack?

Author: BartoliniMarco, FalsettiLorenzo, SilvestriniMauro, ViticchiGiovanna

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Migraines are severe headaches that can be debilitating. This article discusses the use of "ditans," a new class of medications for treating migraines, and focuses on lasmiditan, a ditan that is currently available for use.
Paper Details　
Original Abstract of the Article :
Migraine attack is characterized by disabling pain and associated symptoms. Triptans represent the "gold standard" therapy, but cardiac subjects have significant limitations for this approach. New drug families are under consideration to expand therapeutic offerings, especially in the presence of co...See full text at original site
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://doi.org/10.1007/s10072-022-06260-z

データ提供：米国国立医学図書館（NLM）

Ditans: A New Frontier in Migraine Therapy?

Migraine attacks are characterized by debilitating pain and associated symptoms. Triptans have long been considered the gold standard therapy, but their use is limited in patients with cardiovascular conditions. This research explores the potential of a new class of drugs, known as 'ditans,' for treating migraine attacks. The review focuses on lasmiditan, a ditan that has been approved for human use. The authors discuss the rationale for developing ditans, considering their distinct mechanism of action and potential advantages over triptans.

Beyond Triptans: Exploring Ditans for Migraine Treatment

The review highlights the emerging role of ditans, a new class of drugs, in migraine treatment. Ditans, like lasmiditan, offer a promising alternative for patients who cannot tolerate triptans or experience inadequate relief from traditional therapies. The review suggests that ditans may provide a more targeted approach to migraine treatment, potentially reducing the risk of cardiovascular side effects.

Navigating the Desert of Migraine Pain: Finding New Paths to Relief

The development of ditans represents a significant advancement in migraine treatment. Like a desert traveler seeking a new route, researchers are exploring innovative ways to alleviate the burden of migraine pain. Ditans hold promise for expanding therapeutic options and improving outcomes for patients with migraine.

Dr. Camel's Conclusion

This review sheds light on the promising future of ditans in migraine treatment. Just as a camel adapts to the harsh desert environment, researchers are constantly seeking new solutions to combat the challenges of migraine. Ditans offer a potential breakthrough, providing hope for a more effective and safer treatment for migraine sufferers.

Date :
  1. Date Completed 2022-08-19
  2. Date Revised 2022-08-19
Further Info :

Pubmed ID

35816257

DOI: Digital Object Identifier

10.1007/s10072-022-06260-z

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・Effects of lasmiditan
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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