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[Tolvaptan in ADPKD patients at the University of Padova Nephrology Unit: impact on quality of life, efficacy and safety].
Author: Baldini AnastasioPaola, BugnottoBeatrice, CalòLorenzo A, CampoDaniela, CarraroGianni, CirellaIrene, RigatoMatteo, di VicoValentina
Original Abstract of the Article :
Autosomal dominant polycystic kidney disease (ADPKD) is responsible of the 10% of the dialysis patients. Tolvaptan is a consolidate option for treatment of ADPKD patients; it slows renal deterioration rate and cysts' growth, although its acquaretic effects often impact on quality of life (QoL) and t...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/35819042
データ提供:米国国立医学図書館(NLM)
Tolvaptan in ADPKD: Navigating the Desert of Kidney Disease
Autosomal dominant polycystic kidney disease (ADPKD) is a relentless condition, akin to a desert slowly swallowing up an oasis. This study investigates the impact of tolvaptan, a drug used to treat ADPKD, on patients' quality of life (QoL), treatment efficacy, and safety. The researchers meticulously analyzed data from 13 patients, evaluating their QoL, renal function, and adverse events before and after starting tolvaptan therapy. Their findings demonstrate that tolvaptan did not significantly impact patients' QoL, despite its diuretic effects, and was associated with a slower rate of renal deterioration. This suggests that tolvaptan could be a valuable tool for managing ADPKD and preserving kidney function.
Tolvaptan: A Potential Oasis in the Desert of ADPKD
The study's findings suggest that tolvaptan could offer a promising treatment option for ADPKD. While the diuretic effects of tolvaptan can be challenging, the researchers found that these effects did not significantly impact patients' QoL. Furthermore, the study demonstrated a slower rate of renal deterioration in patients receiving tolvaptan, suggesting that this drug could be a valuable tool for preserving kidney function and delaying the progression of ADPKD.
Living with ADPKD: Understanding the Potential Benefits of Tolvaptan
This research provides valuable insights for individuals living with ADPKD. The study's findings suggest that tolvaptan could offer a potential path to manage the disease and preserve kidney function, without significantly impacting QoL. However, further research is needed to confirm these findings and to fully understand the long-term effects of tolvaptan in a larger patient population.
Dr. Camel's Conclusion
Living with ADPKD can be a challenging journey through a desert landscape. This study suggests that tolvaptan could offer a vital oasis, providing a potential path to manage the disease and preserve kidney function without significantly impacting patients' QoL. While further research is necessary, tolvaptan holds promise as a valuable tool for those facing the complexities of ADPKD.
Date :
- Date Completed 2022-07-13
- Date Revised 2022-07-13
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