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Long-Term Safety, Tolerability and Survival in Patients with Pulmonary Arterial Hypertension Treated with Macitentan: Results from the SERAPHIN Open-Label Extension.
Author: BoyanovaNeli, ChamitavaLiliya, ChannickRichard N, DelcroixMarion, GaliéNazzareno, JansaPavel, MehtaSanjay, PulidoTomás, RubinLewis, SastryB K S, SimonneauGérald, SitbonOlivier, SouzaRogério, SteinClaudia, TorbickiAdam
Original Abstract of the Article :
In SERAPHIN, a long-term, event-driven, double-blind randomised controlled trial in pulmonary arterial hypertension (PAH), macitentan 10 mg significantly reduced the risk of morbidity/mortality compared with placebo. Its open-label extension study (SERAPHIN OL) further assessed long-term safety and ...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402744/
データ提供:米国国立医学図書館(NLM)
Long-Term Safety and Tolerability of Macitentan in Pulmonary Arterial Hypertension
Pulmonary arterial hypertension (PAH) is a serious condition, much like a formidable desert storm that can quickly overwhelm a traveler. The quest for effective and safe treatments for PAH is a constant journey, akin to a camel caravan searching for a safe haven. This study delves into the long-term safety and tolerability of macitentan, a medication used to treat PAH, by examining data from the SERAPHIN open-label extension study. The researchers, like seasoned explorers, meticulously analyzed the data to uncover the long-term effects of this medication.
Macitentan Demonstrates Long-Term Safety and Tolerability
The results, like a steady oasis in the heart of a vast desert, show that macitentan continues to be a safe and well-tolerated treatment option for patients with PAH. The study found no significant new safety concerns associated with long-term use of this medication. This finding is particularly encouraging, as it provides reassurance to both patients and physicians.
Navigating the Treatment Landscape with Confidence
This study, like a trusted guide leading a caravan through the desert, provides valuable information for patients and doctors navigating the challenging treatment landscape of PAH. The data suggest that macitentan can be a long-term solution, offering both safety and effectiveness. This knowledge empowers patients and doctors to make informed decisions about treatment, offering a sense of confidence and stability in the face of a potentially overwhelming condition.
Dr. Camel's Conclusion
The SERAPHIN open-label extension study on macitentan provides a crucial piece of the puzzle in understanding the long-term effects of this medication. This research not only confirms the safety and tolerability of macitentan but also offers hope for patients seeking a long-term solution for their PAH. This is a beacon of light in the often-difficult journey of managing this complex condition.
Date :
- Date Completed 2022-08-26
- Date Revised 2022-09-23
Further Info :
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