Paper Details 
Original Abstract of the Article :
Label="INTRODUCTION" NlmCategory="UNASSIGNED">Fruits of <i>Ammi majus</i>, commonly called bishop's weed, contain a significant amount of furanocoumarins. Alloimperatorin (Allo, <b>6</b>) was isolated from the free coumarin fraction of fruits, beside 8-hydroxypsoralen (<b>1</b>), methoxsalen (<b>2</...See full text at original site
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引用元:
https://doi.org/10.1080/1354750X.2022.2102213

データ提供:米国国立医学図書館(NLM)

Alloimperatorin's Protective Effects Against Piroxicam-Induced Toxicity

Piroxicam, a nonsteroidal anti-inflammatory drug (NSAID), is widely used to relieve pain and inflammation. However, piroxicam can cause serious side effects, including gastric ulcers and damage to the liver and kidneys. This research explores the potential of alloimperatorin, a compound found in the fruit of the bishop's weed plant, to protect against piroxicam-induced toxicity. Researchers investigated the effects of alloimperatorin on piroxicam-induced gastric ulcers, liver damage, and kidney damage in rats.

A Natural Shield: Alloimperatorin's Protective Effects Against Piroxicam Toxicity

The study found that alloimperatorin significantly reduced the severity of piroxicam-induced gastric ulcers, liver damage, and kidney damage in rats. Alloimperatorin's protective effects were attributed to its ability to suppress oxidative stress and apoptosis, processes that contribute to cell damage. Think of alloimperatorin as a natural shield, protecting the body from the harmful effects of piroxicam.

Harnessing Nature's Power: Potential Applications for Alloimperatorin

This research highlights the potential of alloimperatorin as a natural protector against the harmful effects of NSAIDs like piroxicam. While further research is needed to confirm these findings in humans, this study suggests that alloimperatorin may have therapeutic potential in reducing the side effects of NSAID use. This research is like a hidden oasis in the desert, revealing the therapeutic potential of natural compounds.

Dr.Camel's Conclusion

This research highlights the potential of alloimperatorin, a natural compound found in bishop's weed, to protect against the harmful effects of piroxicam. The study's findings suggest that alloimperatorin may offer a natural solution to reduce the side effects of NSAID use, particularly for individuals seeking to manage pain and inflammation without experiencing the risks associated with these medications. This research, like a treasure trove in the desert, offers a glimpse into the potential of nature to provide solutions for human health challenges.

Date :
  1. Date Completed 2022-11-21
  2. Date Revised 2022-11-21
Further Info :

Pubmed ID

35837760

DOI: Digital Object Identifier

10.1080/1354750X.2022.2102213

Related Literature

SNS
PICO Info
in preparation
Languages

English

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