Adverse events of metronidazole and amoxicillin: Retrospective analysis of a large data set of five randomized clinical trials.

Author: BorgesIvan, Castro Dos SantosNidia, DuartePoliana Mendes, FaveriMarcelo, FeresMagda, FigueiredoLuciene C, GiudicissiMarcela, GraçasYasmin Teixeira das, MestnikMaria Josefa, MirandaTamires S, MoniqueSarah, PannutiClaudio Mendes, Pereira da SilvaHélio Doyle, Retamal-ValdesBelen, RomitoGiuseppe Alexandre, SaraivaLuciana, SoaresGeisla Mary Silva, SoutoMaria Luisa Silveira, TavaresAna Paula Laranjeira

Paper Details 
Original Abstract of the Article :
AIM: To evaluate the frequency of side effects associated with intake of metronidazole (MTZ) + amoxicillin (AMX) in periodontal treatment, and to explore associations between these events and patients' features. MATERIALS AND METHODS: Data of five randomized clinical trials testing MTZ + AMX adjunc...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1111/jcpe.13704

データ提供:米国国立医学図書館(NLM)

Unveiling the Side Effects of Metronidazole and Amoxicillin

This research delves into the world of pharmaceuticals, exploring the potential side effects of a common antibiotic combination, metronidazole and amoxicillin, often used in dental treatment. Imagine these antibiotics like a team of explorers navigating the intricate landscape of your body, battling harmful bacteria. This study, like a careful cartographer mapping the terrain, analyzed data from five clinical trials involving 656 patients. The researchers found that the most common side effects of this antibiotic combination were diarrhea and a metallic taste, which are like unexpected detours on the journey to health. The study also found that certain patient characteristics, like diabetes, increased the likelihood of experiencing side effects, as if the terrain became more treacherous for individuals with specific conditions.

Antibiotics: A Double-Edged Sword

This study highlights the importance of understanding the potential risks associated with antibiotic use. While antibiotics are a powerful tool in fighting bacterial infections, they are not without their drawbacks. The researchers found that the frequency of side effects ranged from uncommon to very common, suggesting that these drugs can significantly affect some patients.

Take Your Antibiotics Wisely

This research suggests that if you're prescribed metronidazole and amoxicillin, it's important to be aware of the potential side effects and discuss your medical history with your doctor. Just as a seasoned explorer prepares for potential obstacles, being informed about the possible side effects of antibiotics can help you navigate the journey to health more effectively. If you do experience any unusual side effects, it's essential to consult with your doctor immediately. This study underscores the importance of careful consideration and informed decision-making when it comes to using antibiotics.

Dr.Camel's Conclusion

This study, like a well-traveled camel caravan, reminds us that antibiotics can be a valuable resource, but require careful navigation. Understanding the potential side effects and discussing your medical history with your doctor are essential for a safe and effective journey to health.

Date :
  1. Date Completed 2022-10-18
  2. Date Revised 2022-11-17
Further Info :

Pubmed ID

35851689

DOI: Digital Object Identifier

10.1111/jcpe.13704

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.