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A combined treatment with selective androgen and estrogen receptor modulators prevents bone loss in orchiectomized rats.

Author: BökerK O, BüchlerG, HoffmannD B, KomrakovaM, LehmannW, RochP J, SchillingA F, SehmischS, TaudienS

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

A combination of enobosarm and raloxifene may improve bone health in orchiectomized rats, suggesting a potential treatment for osteoporosis.
Paper Details　
Original Abstract of the Article :
Enobosarm (EN), a selective androgen receptor modulator and raloxifene (RAL), a selective estrogen receptor modulator, have been shown to improve bone tissue in osteoporotic males. The present study evaluated the effects of a combination therapy of EN and RAL on bone properties in orchiectomized rat...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646546/

データ提供：米国国立医学図書館（NLM）

Combating Bone Loss: A Combined Approach with Selective Androgen and Estrogen Receptor Modulators

Bone loss is a significant concern, particularly for individuals at risk of osteoporosis. This research is like a scientist meticulously mixing ingredients in a laboratory, exploring the effects of a combined therapy with selective androgen receptor modulator (EN) and selective estrogen receptor modulator (RAL) on bone properties in orchiectomized rats. The authors demonstrate the potential of this combination therapy to prevent bone loss, offering a promising new strategy for bone health management.

Combined Therapy for Bone Loss: A Promising New Approach

This research suggests that a combined therapy with EN and RAL might be an effective strategy to prevent bone loss. This is like finding a rare oasis in a vast desert, offering a potential solution to a challenging problem.

Strengthening Bones: A Multifaceted Approach

This research highlights the potential benefits of a combined therapy with EN and RAL for bone health. It emphasizes the need for a multifaceted approach to preventing and treating bone loss, considering the unique needs of each individual. This is like a caravan navigating a desert, carefully considering the terrain and resources available to ensure a safe and successful journey.

Dr.Camel's Conclusion

This research demonstrates the potential benefits of a combined therapy with EN and RAL to prevent bone loss in orchiectomized rats. This study is like a desert traveler who has discovered a new source of water, offering hope for individuals concerned about bone health.
Date :
  1. Date Completed 2022-11-11
  2. Date Revised 2022-11-16
Further Info :

Pubmed ID

35867330

DOI: Digital Object Identifier

PMC9646546

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SNS
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in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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