Paper Details 
Original Abstract of the Article :
Aluminum hydroxide nanoparticles have been employed in many industries, which are widely abundant in many aspects of human life. The role of the aluminum hydroxide nanoparticles adjuvant is to enhance the immune response. However, the impact of nanoparticles exposure has not been perfectly investiga...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288589/

データ提供:米国国立医学図書館(NLM)

Aluminum Hydroxide Nanoparticles: A Closer Look at Their Potential Toxicity

Aluminum hydroxide nanoparticles are widely used as adjuvants in vaccines, boosting the immune response. However, concerns have been raised about their potential toxicity. This study aimed to investigate the histological effects of aluminum hydroxide nanoparticles on various tissues in neonatal mice, comparing their impact to bulk-aluminum hydroxide.

Navigating the Desert of Nanoparticle Toxicity

The study revealed that both aluminum hydroxide nanoparticles and bulk-aluminum hydroxide caused pathological lesions in the liver, lung, heart, and kidney tissues of neonatal mice. However, bulk Al (OH)3 adjuvant vaccine had a more pronounced pathological response than aluminum hydroxide nanoparticles adjuvant vaccine. These findings highlight the need for ongoing research to better understand the potential risks associated with nanoparticles and to develop safer alternatives.

A Journey Through the Desert of Nanotechnology

This study, like a desert explorer cautiously venturing into uncharted territory, provides valuable insights into the potential risks associated with nanoparticles. The research underscores the importance of carefully considering the potential consequences of using nanoparticles, especially in vulnerable populations, and emphasizes the need for ongoing research to ensure the safety and efficacy of nanotechnology applications.

Dr.Camel's Conclusion

This study, like a desert explorer encountering a hidden oasis, reveals important information about the potential toxicity of aluminum hydroxide nanoparticles. The research highlights the importance of ongoing research to assess the safety and efficacy of nanotechnology applications, particularly in vulnerable populations, ensuring a safe and responsible journey through the vast desert of nanotechnology.

Date :
  1. Date Completed 2022-07-28
  2. Date Revised 2022-08-15
Further Info :

Pubmed ID

35891766

DOI: Digital Object Identifier

PMC9288589

Related Literature

SNS
PICO Info
in preparation
Languages

English

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