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Capecitabine-related neurotoxicity presenting with agraphia.

Author: BayramErtugrul, BicakciSebnem, DemirTurgay, IscanDilek, TolayRumeysa

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.

Overview

This study describes a case of a patient who developed neurological side effects from capecitabine treatment. Capecitabine is a chemotherapy drug that is used to treat a variety of cancers. The researchers found that the patient developed agraphia and dysarthria, which are neurological disorders that affect writing and speech.
Paper Details　
Original Abstract of the Article :
Capecitabine is a pre-metabolite of 5-fluorouracil and is used as a chemotherapeutic agent. Among the common side effects of capecitabine, there are gastrointestinal side effects including nausea, vomiting, and diarrhea, and dermatological side effects including hand-foot syndrome and skin pigmentat...See full text at original site
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引用元：
https://doi.org/10.1177/10781552221116329

データ提供：米国国立医学図書館（NLM）

Capecitabine-Related Neurotoxicity

The field of cancer treatment is constantly evolving, with new drugs and therapies emerging to combat this formidable foe. Capecitabine, a pre-metabolite of 5-fluorouracil, is one such agent used in chemotherapy. While it is generally well-tolerated, it can sometimes have rare and unexpected side effects. This case report describes a patient who developed neurotoxicity in the form of agraphia (inability to write) and dysarthria (difficulty speaking) on the 7th day of capecitabine treatment.

A Case of Neurotoxicity

The case report highlights the importance of being vigilant about potential side effects, even those that are rarely encountered. It is like navigating a vast desert – unexpected challenges can arise, and it's essential to have a plan to address them.

Navigating the Treatment Landscape

This report provides valuable insight into the complex interplay between cancer treatment and potential neurological complications. Doctors and patients need to be aware of these rare but potentially serious side effects.

Dr. Camel's Conclusion

This case report underscores the importance of being prepared for the unexpected when it comes to cancer treatment. Like a desert traveler who must be ready for any obstacle, healthcare providers should stay informed about potential side effects and be ready to adapt treatment plans as needed.

Date :
  1. Date Completed 2023-04-03
  2. Date Revised 2023-04-03
Further Info :

Pubmed ID

35903929

DOI: Digital Object Identifier

10.1177/10781552221116329

Related Literature

Article Analysis
・Side Effects of capecitabine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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