Paper Details 
Original Abstract of the Article :
Adrenaline is the drug of choice for management of the anaphylactic reaction. The objective of this study was to compare systemic absorption of adrenaline after administration by different routes to healthy volunteers. Ten puffs (1.5 mg as adrenaline base) with 10-15 s intervals between them followe...See full text at original site
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引用元:
https://doi.org/10.1111/j.1398-9995.1987.tb02202.x

データ提供:米国国立医学図書館(NLM)

Systemic Absorption of Adrenaline: A Journey Through Different Routes

Imagine a camel caravan traversing the vast desert. Each route presents unique challenges and opportunities. Similarly, adrenaline, the drug of choice for managing anaphylactic reactions, shows varying levels of systemic absorption depending on how it's administered. In this study, researchers compared the absorption of adrenaline after it was delivered through the following routes: inhalation, eye drops, and subcutaneous injection.

Adrenaline's Journey: A Tale of Absorption

The study found that administering adrenaline as eye drops had no significant effect on systemic absorption. However, subcutaneous administration led to a significant increase in plasma adrenaline levels, accompanied by changes in blood pressure, heart rate, and tremor. The results highlight the variability in adrenaline absorption depending on the delivery route.

Understanding Adrenaline's Impact

Adrenaline is a powerful drug that plays a vital role in managing anaphylactic reactions, a life-threatening allergic response. Understanding how adrenaline is absorbed depending on the delivery route is crucial for optimizing treatment strategies. It's like knowing the best path to navigate through a desert, ensuring the safe and efficient delivery of vital resources.

Dr. Camel's Conclusion

This research sheds light on the fascinating journey of adrenaline through our bodies. By understanding the different routes of administration and their impact on systemic absorption, we can better manage allergic reactions and ensure the safety and effectiveness of this crucial medication.

Date :
  1. Date Completed 1987-07-16
  2. Date Revised 2019-08-20
Further Info :

Pubmed ID

3592145

DOI: Digital Object Identifier

10.1111/j.1398-9995.1987.tb02202.x

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SNS
PICO Info
in preparation
Languages

English

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