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Role of human papillomavirus (HPV) vaccination on HPV infection and recurrence of HPV related disease after local surgical treatment: systematic review and meta-analysis.

Author: AthanasiouAntonios, BowdenSarah J, DillnerJoakim, KallialaIlkka, KechagiasKonstantinos S, KyrgiouMaria, NieminenPekka, ParaskevaidiMaria, ParaskevaidisEvangelos, SasieniPeter, StranderBjorn, VeronikiAreti Angeliki

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

HPV vaccination might reduce the risk of cervical intraepithelial neoplasia (CIN) recurrence, especially when related to HPV16 or HPV18, in women treated with local excision. The risk of CIN2+ recurrence was reduced by 57% in vaccinated women compared to unvaccinated women (risk ratio 0.43, 95% confidence interval 0.30 to 0.60). However, large-scale, high-quality randomized controlled trials are needed to confirm this finding and establish the effectiveness and cost of HPV vaccination in women undergoing treatment for HPV-related diseases.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To explore the efficacy of human papillomavirus (HPV) vaccination on the risk of HPV infection and recurrent diseases related to HPV infection in individuals undergoing local surgical treatment. DESIGN: Systematic review and meta-analysis DATA SOURCES: PubMed (Medline), Scopus, Cochrane,...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347010/

データ提供：米国国立医学図書館（NLM）

Exploring the Role of HPV Vaccination in Preventing HPV Infection and Recurrence after Local Surgical Treatment

This study delves into the potential benefits of human papillomavirus (HPV) vaccination in individuals undergoing local surgical treatment for HPV-related diseases. The study aims to determine the efficacy of HPV vaccination in preventing HPV infection and recurrence of HPV-related disease after surgical treatment. The study utilizes a systematic review and meta-analysis approach to synthesize the available evidence.

HPV Vaccination: A Promising Strategy for Preventing Recurrence

The study's findings suggest that HPV vaccination may significantly reduce the risk of recurrence of HPV-related disease after local surgical treatment. While the evidence is inconclusive due to limitations in available studies, the results are encouraging and warrant further investigation. The researchers highlight the need for large-scale randomized controlled trials to definitively assess the efficacy of HPV vaccination in this context.

A Beacon of Hope in the Desert of HPV-Related Diseases

This study provides a glimmer of hope in the fight against HPV-related diseases. The potential of HPV vaccination to prevent recurrence after surgical treatment is a significant finding. It's like discovering a new source of water in a vast desert, offering a ray of hope to those battling these challenging conditions. As a researcher, I am passionate about finding new ways to prevent and treat diseases, and this study highlights the importance of vaccination in achieving this goal.

Dr.Camel's Conclusion

This study explores the potential benefits of HPV vaccination in preventing HPV infection and recurrence after local surgical treatment for HPV-related diseases. While further research is needed, the study's findings suggest that HPV vaccination could play a significant role in reducing the risk of recurrence. It's a reminder that ongoing research and innovation are essential in the fight against these diseases.

Date :
  1. Date Completed 2022-08-05
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

35922074

DOI: Digital Object Identifier

PMC9347010

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・Effective treatment of hpv
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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