Oral cannabidiol for prevention of acute and transient chemotherapy-induced peripheral neuropathy.

Author: DaltonSusanne Oksbjerg, DominiakHelena Sylow Heilmann, HasselsteenSimone Dyring, HerrstedtJørn, LabudovicDejan, NielsenSebastian W, ReiterLars

Paper Details 
Original Abstract of the Article :
PURPOSE: To assess the safety, dosing, and preventive effects of cannabidiol (CBD) on chemotherapy-induced peripheral neuropathy (CIPN) in patients receiving oxaliplatin- or paclitaxel-based chemotherapy. METHODS: Patients with cancer scheduled to undergo treatment with carboplatin and paclitaxel (...See full text at original site
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引用元:
https://doi.org/10.1007/s00520-022-07312-y

データ提供:米国国立医学図書館(NLM)

Cannabidiol: A Potential Oasis in the Desert of Chemotherapy-Induced Peripheral Neuropathy

The [management of chemotherapy-induced peripheral neuropathy (CIPN)] is a significant challenge for cancer patients. This research explores the potential of [oral cannabidiol (CBD)] in [preventing CIPN] in patients receiving oxaliplatin- or paclitaxel-based chemotherapy. The study investigated the [safety and efficacy of CBD] in a group of patients receiving chemotherapy, assessing [CIPN-specific patient-reported outcomes] and [multi-frequency vibrometry] to evaluate the impact of CBD on nerve function. Key findings include [a reduction in early symptoms of CIPN] in patients receiving CBD, suggesting its potential as a preventive agent.

A New Path Through the Desert: Exploring Cannabidiol for CIPN

This research offers exciting insights into the potential of [CBD] as a [preventive therapy] for CIPN. The study found that [CBD treatment] was associated with [a significant reduction in early CIPN symptoms], suggesting its potential to [mitigate the debilitating effects] of this common chemotherapy side effect. This information encourages further research into the [long-term effects of CBD] and its [potential to improve the quality of life] for patients undergoing chemotherapy.

A Desert of Discomfort: Seeking Relief from CIPN

This research offers hope for patients facing the challenges of [CIPN]. The study suggests that [CBD] may offer [a new avenue for prevention], potentially [reducing the severity of symptoms] and improving [the overall experience of chemotherapy] for these individuals. It underscores the importance of [exploring novel therapeutic approaches] to address this debilitating side effect and [improve the quality of life] for cancer patients.

Dr.Camel's Conclusion

This study provides promising evidence for the potential of CBD in preventing early symptoms of CIPN. While further research is needed to confirm these findings and explore long-term effects, this research offers hope for a new approach to managing this challenging side effect of chemotherapy.

Date :
  1. Date Completed 2022-11-07
  2. Date Revised 2022-11-07
Further Info :

Pubmed ID

35933415

DOI: Digital Object Identifier

10.1007/s00520-022-07312-y

Related Literature

SNS
PICO Info
in preparation
Languages

English

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