Oral isotretinoin for acne vulgaris side effects on the ocular surface: Hyaluronic acid and galacto-xyloglucan as treatment for dry eye disease signs and symptoms.

Combating Dry Eye: A New Approach to Isotretinoin-Induced Ocular Surface Complications

The desert of dry eye disease can be a harsh and unforgiving landscape, causing discomfort and affecting quality of life. This study explores a potential oasis in this arid terrain, evaluating the efficacy of hyaluronic acid and galacto-xyloglucan for treating dry eye symptoms associated with oral isotretinoin therapy for acne vulgaris. The researchers conducted a prospective, longitudinal study to compare the effects of hyaluronic acid with galacto-xyloglucan (HA-GX) to hyaluronic acid alone (HA) on dry eye signs and symptoms.

HA-GX: A Powerful Duo for Dry Eye Relief

The results revealed that HA-GX demonstrated superior efficacy in reducing subjective dry eye symptoms and improving both invasive and non-invasive tear film parameters. Patients receiving HA-GX experienced a greater decrease in ocular surface disease index and standard patient evaluation of eye dryness scores compared to those receiving HA alone. HA-GX also led to a significant improvement in non-invasive break-up time and a reduction in limbal and bulbar conjunctival redness.

Hope for Isotretinoin Users

This research suggests that HA-GX may offer a promising therapeutic option for treating dry eye disease associated with oral isotretinoin therapy. The findings provide valuable insights into the potential benefits of combining hyaluronic acid with galacto-xyloglucan for alleviating dry eye symptoms and improving ocular surface health.

Dr.Camel's Conclusion

This study offers hope for individuals experiencing dry eye symptoms associated with isotretinoin therapy. HA-GX emerged as a potential oasis in the desert of dry eye, offering a promising approach to combatting this uncomfortable condition. The research provides valuable insights into the potential of HA-GX to improve ocular surface health and enhance the overall well-being of patients using isotretinoin for acne vulgaris.