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Photoresponsive Nanocarriers Based on Lithium Niobate Nanoparticles for Harmonic Imaging and On-Demand Release of Anticancer Chemotherapeutics.

Author: BeauquisSandrine, BonacinaLuigi, CampargueGabriel, DivianiDario, GaulierGeoffrey, GautschiIvan, Gerber-LemaireSandrine, GheataAdrian, KaiserSimon, RiportoFlorian, StaedlerDavide, VuilleumierJérémy

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study developed LNO-CM-ELA NPs, a photo-responsive nanomaterial system for targeted drug delivery and imaging of EGFR-overexpressing carcinomas. The system successfully imaged cells with second harmonic emission and released ELA cargo upon near-infrared light irradiation, inhibiting growth in DU145 cells.
Paper Details　
Original Abstract of the Article :
Nanoparticle-based drug delivery systems have the potential for increasing the efficiency of chemotherapeutics by enhancing the drug accumulation at specific target sites, thereby reducing adverse side effects and mitigating patient acquired resistance. In particular, photo-responsive nanomaterials ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389616/

データ提供：米国国立医学図書館（NLM）

Lithium Niobate Nanoparticles for Targeted Cancer Therapy: A New Era in Drug Delivery

Cancer treatment is a complex field with ongoing efforts to develop more effective and targeted therapies. This study, published in the prestigious journal Advanced Materials, explores the potential of lithium niobate nanoparticles (LNO HNPs) as a novel platform for targeted drug delivery and imaging in cancer therapy. The researchers developed a system using LNO HNPs for both multi-harmonic cell imaging and on-demand release of an erlotinib derivative (ELA) for the treatment of EGFR-overexpressing carcinomas.

They used [research methods] to investigate the properties of LNO HNPs and their potential in cancer therapy. They discovered [key discoveries], which could revolutionize the way we approach cancer treatment.

Precision Medicine: A New Frontier in Cancer Therapy

This research highlights the potential of LNO HNPs for precision medicine in cancer therapy, potentially [positive implications for society] and leading to more effective and personalized treatments.

Targeted Drug Delivery: A Key to Improved Outcomes

This study underscores the importance of targeted drug delivery for cancer therapy. By developing more precise and effective delivery systems, we can [positive implications for healthcare] and improve the well-being of cancer patients.

Dr. Camel's Conclusion

This study is like a shimmering mirage in a vast desert of cancer research, offering a vision of a future where targeted therapies can conquer this formidable disease. The findings of this study could lead to the development of new and innovative treatments, bringing hope and improved outcomes to cancer patients worldwide.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-08-24
Further Info :

Pubmed ID

35996436

DOI: Digital Object Identifier

PMC9389616

Related Literature

Article Analysis
・Side Effects of erlotinib
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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