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Variability in Serum Concentrations and Clinical Response in Artisanal Versus Pharmaceutical Cannabidiol Treatment of Pediatric Pharmacoresistant Epilepsy.
Author: BaharBurak, CohenNathan T, ConryJoan A, SchreiberJohn M
Original Abstract of the Article :
OBJECTIVE: We hypothesized that serum cannabidiol (CBD) concentrations would be higher in patients taking pharmaceutical- versus artisanal-CBD oil, and higher serum CBD concentrations would correlate with increased side effects and decreased seizure frequency. METHODS: This was a retrospective char...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400177/
データ提供:米国国立医学図書館(NLM)
Cannabidiol: A Complex Landscape of Treatment Options
The field of [neurology] is increasingly exploring the potential of [cannabidiol (CBD)] in treating [pharmacoresistant epilepsy]. This research investigates the [serum concentrations and clinical response] to [artisanal versus pharmaceutical CBD] in [pediatric patients]. The study found that [pharmaceutical CBD achieves higher serum concentrations] than [artisanal CBD] and that [higher CBD concentrations are associated with increased reported adverse effects]. However, the study did not find a significant difference in [seizure frequency] between the two groups.
A Complex Landscape of Cannabidiol Treatment
The study emphasizes the importance of [understanding the varying concentrations and potential side effects] of [different CBD formulations]. It underscores the need for [further research] to determine the optimal [dosage and treatment strategies] for individual patients.
The Desert of Epilepsy: Navigating Treatment Options
Epilepsy can feel like a vast and unpredictable desert, with seizures acting like unpredictable sandstorms. This research helps us navigate the complexities of CBD treatment for this condition, revealing important insights into the variations between different formulations and their potential impact on patients.
Dr.Camel's Conclusion
This study highlights the evolving landscape of CBD treatment for epilepsy, emphasizing the need for careful consideration of the dosage, formulation, and potential side effects. As researchers continue to explore the therapeutic potential of CBD, it's crucial to approach this treatment with a balanced perspective, weighing its benefits against its risks and ensuring that patients receive the most appropriate and effective care.
Date :
- Date Completed n.d.
- Date Revised 2022-09-06
Further Info :
Related Literature
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