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Monoamine-oxidase Type B Inhibitors and Cognitive Functions in Parkinson's Disease: Beyond the Primary Mechanism of Action.
Author: AlborghettiMarika, BianchiniEdoardo, GalliSilvia, PontieriFrancesco E, RinaldiDomiziana, SforzaMichela
Original Abstract of the Article :
Symptoms of cognitive impairment are rather common since the early stage of Parkinson's disease (PD); they aggravate with disease progression and may lead to dementia in a significant proportion of cases. Worsening of cognitive symptoms in PD patients depends on the progression of subcortical dopami...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286595/
データ提供:米国国立医学図書館(NLM)
Monoamine-oxidase Type B Inhibitors and Cognitive Functions in Parkinson's Disease
Parkinson's disease (PD) is a neurodegenerative disorder that affects movement, cognition, and other bodily functions. This review explores the impact of monoamine-oxidase type B inhibitors (MAOB-I) on cognitive functions in PD patients. It examines the potential benefits and drawbacks of these medications, focusing on their effects on different cognitive domains. The authors analyze the results of available studies to provide a comprehensive overview of the current understanding of MAOB-I's role in PD treatment.
MAOB-I: A Balancing Act in Parkinson's Disease
The review highlights the complex relationship between MAOB-I and cognition in PD. It suggests that these medications may offer benefits for certain cognitive functions, particularly in early stages of the disease. However, the review also notes that MAOB-I may have negative impacts on other cognitive domains, particularly in more advanced stages. This research underscores the need for a nuanced understanding of MAOB-I's effects on cognition in PD, taking into account factors such as disease stage and individual patient characteristics.
Navigating the Treatment Landscape of Parkinson's Disease
The review's insights provide valuable guidance for healthcare providers treating PD patients. It emphasizes the importance of carefully considering the potential benefits and risks of MAOB-I treatment, taking into account the patient's individual needs and disease stage. The review's findings underscore the need for ongoing research to further refine and optimize treatment strategies for PD, ultimately improving the quality of life for patients with this debilitating disease.
Dr.Camel's Conclusion
This review delves into the intricate relationship between MAOB-I and cognitive function in PD. It's like navigating a desert oasis – a complex ecosystem where different elements interact. Understanding these interactions is crucial for effective treatment and improved patient outcomes. The review serves as a reminder that navigating the treatment landscape of PD requires a delicate balance, taking into account the unique needs of each patient and the complex interplay of different therapeutic approaches.
Date :
- Date Completed 2023-05-22
- Date Revised 2023-10-13
Further Info :
Related Literature
English
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