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A case of linezolid-induced SIADH in elderly and a review of the literature.

Author: DongQ-W, GeD-D, MaC-H, SunP, TangL, ZhaoY-C, ZhouT-Y

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

A case of syndrome of inappropriate antidiuretic hormone (SIADH) was reported after starting linezolid treatment.
Paper Details　
Original Abstract of the Article :
Linezolid is a synthetic oxazolidinone antimicrobial drug with a broad spectrum and a unique mechanism of inhibiting resistant pathogenic strains, and it was approved by the Food and Drug Administration (FDA) in April 2000. Several different systemic side effects were reported after the use of this ...See full text at original site
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引用元：
https://doi.org/10.26355/eurrev_202208_29505

データ提供：米国国立医学図書館（NLM）

Linezolid-Induced SIADH: A Case Report and Literature Review

This study examines a case of linezolid-induced syndrome of inappropriate antidiuretic hormone (SIADH), a potentially life-threatening condition characterized by fluid retention and hyponatremia. The study provides a comprehensive overview of the side effects associated with linezolid, a broad-spectrum antibiotic. The case report highlights the importance of monitoring patients closely for potential complications, particularly in vulnerable populations like the elderly.

Linezolid: A Potentially Hazardous Antibiotic?

This case report and literature review underscore the importance of being aware of the potential side effects of linezolid, including the possibility of developing SIADH. Close monitoring of patients, especially those at higher risk, is crucial to identify and manage any complications.

Navigating the Risks and Benefits of Antibiotic Therapy

The study serves as a reminder that antibiotic therapy can sometimes have unintended consequences. It's crucial to weigh the potential benefits of antibiotic treatment against the risks of side effects, especially in vulnerable populations like the elderly.

Dr. Camel's Conclusion

This case report and literature review raise awareness about the potential risks associated with linezolid therapy, particularly the development of SIADH. The study emphasizes the importance of careful monitoring and early intervention to minimize the potential for serious complications.
Date :
  1. Date Completed 2022-09-08
  2. Date Revised 2022-12-14
Further Info :

Pubmed ID

36066143

DOI: Digital Object Identifier

10.26355/eurrev_202208_29505

Related Literature

Article Analysis
・Side Effects of linezolid
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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