Solriamfetol treatment of excessive daytime sleepiness in participants with narcolepsy or obstructive sleep apnea with a history of depression.

Author: BabsonKimberly, BencaRuth M, BujanoverShay, KrystalAndrew D, LeeLawrence, MalhotraAtul, RosenbergRussell, SchweitzerPaula K, StrohlKingman P

Paper Details 
Original Abstract of the Article :
Given the high rate of depression associated with narcolepsy or obstructive sleep apnea (OSA), this analysis compared effects of solriamfetol treatment of excessive daytime sleepiness (EDS) in participants with/without a history of depression (DHx+/DHx-). This secondary analysis included data from t...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/36070638

データ提供:米国国立医学図書館(NLM)

Solriamfetol for Excessive Daytime Sleepiness: A Study Addressing Depression in Narcolepsy and Obstructive Sleep Apnea

In the realm of sleep disorders, like a vast desert where researchers tirelessly seek to improve sleep quality and alleviate daytime sleepiness, depression often complicates treatment. This study, a meticulous exploration into the effectiveness of solriamfetol, a wakefulness-promoting agent, investigates its impact on excessive daytime sleepiness (EDS) in individuals with narcolepsy and obstructive sleep apnea (OSA), particularly those with a history of depression.

The researchers, like skilled desert navigators, conducted a secondary analysis of data from two randomized controlled trials, meticulously examining the effects of solriamfetol on EDS in individuals with and without a history of depression. Their findings, like oases in the desert, suggest that solriamfetol, like a well-balanced camel caravan, may offer a promising treatment option for EDS, regardless of depression history.

Solriamfetol: A Potential Solution for EDS in Sleep Disorders

The study, like a beacon in the desert, reveals that solriamfetol demonstrated significant improvements in EDS symptoms in individuals with narcolepsy and OSA, regardless of their depression history. This research, like a carefully curated map, guides us toward a better understanding of the potential benefits and risks of using solriamfetol for EDS in these conditions.

Navigating the Complexities of Sleep Disorders

The study, like a compass guiding us through the complexities of sleep disorders, highlights the importance of addressing depression as a critical aspect of patient care. This research underscores the need for continued research and development of effective therapies for treating EDS in individuals with narcolepsy and OSA, regardless of their mental health status.

Dr. Camel's Conclusion

This study, like a camel caravan traversing the sands, provides valuable insights into the effectiveness of solriamfetol for EDS in individuals with narcolepsy and OSA, regardless of depression history. By understanding the potential benefits and risks of this medication, we can better navigate the landscape of sleep disorder treatment and provide our patients with the best possible care.

Date :
  1. Date Completed 2022-10-18
  2. Date Revised 2023-05-02
Further Info :

Pubmed ID

36070638

DOI: Digital Object Identifier

NIHMS1836085

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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