Comparative investigation between thiethylperazine and meclizine in vertigo of different genesis.

Author: JungertS

Paper Details 
Original Abstract of the Article :
Forty patients suffering from vertigo of different genesis received thiethylperazine 6.5 mg or meclizine 25 mg, 2 capsules a day for 5 days, according to double-blind, cross-over methodology in randomized order. It appeared that the effect on the symptoms vertigo, gait disturbance and nausea does no...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/360766

データ提供:米国国立医学図書館(NLM)

Thiethylperazine vs. Meclizine: A Head-to-Head Showdown for Vertigo Relief

Vertigo, a sensation of dizziness and disorientation, can be a real nuisance. This research compares the effectiveness of [thiethylperazine] and [meclizine], two medications commonly used for [vertigo relief]. The authors conducted a [double-blind, cross-over trial] to assess the efficacy of these medications in treating vertigo of different origins.

Similar Efficacy for Vertigo, Nausea, and Gait Disturbances

The study found no statistically significant differences in the effectiveness of thiethylperazine and meclizine for treating [vertigo, gait disturbance, and nausea]. While both medications were [effective], the study found a [statistically significant] reduction in symptoms during the second treatment period, regardless of which medication was administered. This suggests that [repeated treatment] may be beneficial for patients.

Meclizine: A Viable Alternative with Fewer Long-Term Risks

The study reports [similar side effects] for both medications, including [fatigue and headache]. However, meclizine emerged as a [potential alternative] to thiethylperazine, particularly for patients at risk of developing [chronic dyskinesia] from long-term thiethylperazine treatment.

Dr.Camel's Conclusion

This study provides valuable insights into the treatment of vertigo, highlighting the efficacy of both thiethylperazine and meclizine. While the two medications offer similar benefits, meclizine stands out as a potential alternative with fewer long-term risks, particularly for patients who require long-term treatment. Further research is needed to better understand the long-term effects of these medications and their potential for personalized treatment strategies.

Date :
  1. Date Completed 1978-12-20
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

360766

DOI: Digital Object Identifier

360766

Related Literature

SNS
PICO Info
in preparation
Languages

English

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