Lacosamide Intoxication-induced Wide QRS Tachycardia Successfully Treated with Veno-arterial Extracorporeal Membrane Oxygenation.

Author: HagiwaraYoshihiro, KadoyaTakashi, KaitoDaiki, KimuraTakuya, KobayashiTakaomi, KoinumaToshitaka, MisumiKayo, NishidaHiroaki, OguraTakayuki, TakaiChihiro, YamadaSo, YoshiiMasami

Paper Details 
Original Abstract of the Article :
Lacosamide is an antiepileptic drug that acts on voltage-gated sodium channels and was approved as an antiepileptic by the Food and Drug Administration in 2008. Although the efficacy and safety of lacosamide have been established in many previous trials, some case reports have shown that it may lead...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183285/

データ提供:米国国立医学図書館(NLM)

Lacosamide Intoxication: A Case of Wide QRS Tachycardia Successfully Treated with Veno-arterial Extracorporeal Membrane Oxygenation

Imagine the vast desert of medical emergencies, where time is of the essence and quick interventions are crucial. This 2022 case report describes a life-threatening cardiac arrhythmia caused by lacosamide intoxication, a rare but serious adverse effect of this antiepileptic drug. The authors highlight the successful treatment of this complex medical emergency using veno-arterial extracorporeal membrane oxygenation (VA-ECMO), a life-support technology that provides temporary heart and lung function. This case report underscores the importance of prompt recognition and management of drug-induced cardiac complications.

VA-ECMO: A Vital Tool for Life-Threatening Cardiac Emergencies

This case report highlights the effectiveness of VA-ECMO in managing a life-threatening cardiac arrhythmia caused by lacosamide intoxication. The authors demonstrate the potential of this life-support technology to stabilize patients with severe cardiac complications. This case underscores the crucial role of VA-ECMO in addressing emergent medical situations and providing a lifeline for patients experiencing critical cardiac events.

Implications for Drug Safety and Patient Monitoring

This case report serves as a reminder of the importance of vigilant drug monitoring and prompt intervention in the event of adverse effects. It highlights the potential for even seemingly safe medications to cause serious complications in certain individuals. This research emphasizes the need for healthcare providers to be aware of the potential risks associated with medications and to closely monitor patients for any signs of adverse reactions.

Dr. Camel's Conclusion

This case report is like a beacon in the vast desert of medical emergencies, demonstrating the importance of timely recognition and effective management of drug-induced cardiac complications. It underscores the vital role of VA-ECMO in providing life-saving support during critical cardiac events. The research reminds us that even seemingly familiar medications can pose unexpected challenges, highlighting the importance of vigilant monitoring and proactive intervention in patient care.

Date :
  1. Date Completed 2023-04-18
  2. Date Revised 2023-05-16
Further Info :

Pubmed ID

36104195

DOI: Digital Object Identifier

PMC10183285

Related Literature

SNS
PICO Info
in preparation
Languages

English

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