Paper Details

  1. Home
  2. Paper Details

Oligo-Fucoidan supplementation enhances the effect of Olaparib on preventing metastasis and recurrence of triple-negative breast cancer in mice.

Author: Al HaqAushia Tanzih, ChenLi-Mei, ChenMichelle Audrey, HsuHsin-Ling, HwangPai-An, LaiYou-Chen, WengYueh-Shan, YangPao-Pao

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Oligo-fucoidan, a sulfated polysaccharide from brown seaweed, exhibits anticancer activity and may enhance the immune surveillance against triple-negative breast cancers (TNBCs). The study explores the potential benefits of using oligo-fucoidan in combination with olaparib, a PARP inhibitor, for TNBC treatment.
Paper Details　
Original Abstract of the Article :
Seaweed polysaccharides have been recommended as anticancer supplements and for boosting human health; however, their benefits in the treatment of triple-negative breast cancers (TNBCs) and improving immune surveillance remain unclear. Olaparib is a first-in-class poly (ADP-ribose) polymerase inhibi...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479298/

データ提供：米国国立医学図書館（NLM）

Boosting the Fight Against Triple-Negative Breast Cancer: A Seaweed Solution?

This study, published in [Journal Name], explores the potential of seaweed polysaccharides, specifically oligo-fucoidan, as a powerful weapon in the battle against triple-negative breast cancer (TNBC). The researchers meticulously investigate the synergistic effects of oligo-fucoidan with olaparib, a potent anti-cancer drug, in inhibiting metastasis and recurrence of TNBC in mice.

The Power of Oligo-Fucoidan in Combating TNBC

The study reveals that oligo-fucoidan, a sulfated polysaccharide derived from brown seaweed, enhances the efficacy of olaparib in preventing metastasis and recurrence of TNBC in mice. This discovery opens up exciting possibilities for integrating natural compounds into cancer treatment strategies.

A Promising Future for Cancer Treatment

This research holds immense promise for developing innovative and effective therapies for TNBC. The findings suggest that combining natural compounds with existing anti-cancer drugs may lead to more potent and targeted treatments, ultimately improving patient outcomes.

Dr. Camel's Conclusion

This study reminds us that the ocean's depths hold a vast and untapped treasure trove of natural compounds with immense medicinal potential. Just as a desert traveler discovers life-sustaining oases, we may find valuable solutions for complex diseases within the ocean's vast expanse.

Date :
  1. Date Completed 2022-09-19
  2. Date Revised 2022-12-28
Further Info :

Pubmed ID

36109724

DOI: Digital Object Identifier

PMC9479298

Related Literature

Article Analysis
・Side Effects of olaparib
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.