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Integrated gut microbiota and metabolomic analysis reveals immunomodulatory effects of Echinacea extract and Astragalus polysaccharides.

Author: ChanYanzi, ChenJiaxin, GhaffarAbdul, HussainRiaz, LiShaochuan, LinRenzhao, ShiDayou, SuYalin, ZhangShiwei

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study found that Echinacea Extract (EE) and Astragalus polysaccharide (APS) can antagonize the effects of immunosuppression in broiler chickens by modulating the disrupted gut microbiota. However, EE might have a bidirectional regulatory function on intestinal health, and further studies are needed to understand the mechanisms of action.
Paper Details　
Original Abstract of the Article :
Immunosuppression in different animals increases the susceptibility of various infections caused by pathogenic microorganisms leading to increase risks posed by antibiotics in different animal farming sectors. Therefore, investigation of the interactions between natural medicines and the intestinal ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478787/

データ提供：米国国立医学図書館（NLM）

Echinacea and Astragalus: A New Approach to Immunosuppression

Immunosuppression can make animals more susceptible to infections, posing a challenge for animal farming. This study explores the potential of Echinacea extract (EE) and Astragalus polysaccharides (APS) to modulate the gut microbiota and improve immune function in immunosuppressed broiler chickens.

Exploring the Desert of Immunosuppression

The study investigates the impact of EE and APS on the gut microbiota of immunosuppressed chickens, hoping to discover a new approach to restoring immune function. The researchers used 16S rRNA and metabolomic analysis to examine the changes in the gut microbiome and metabolic pathways.

A Potential Oasis in the Desert of Immunosuppression

The study suggests that both EE and APS can modulate the gut microbiota and antagonize the effects of immunosuppression in broiler chickens. This finding suggests that these natural remedies could offer a promising approach to improving immune function in animals, potentially paving the way for safer and more sustainable farming practices.

Dr. Camel's Conclusion

This study provides valuable insights into the potential of Echinacea extract and Astragalus polysaccharides to improve immune function in immunosuppressed animals. The findings suggest that these natural remedies could offer a promising approach to mitigating the negative effects of immunosuppression, leading to healthier and more resilient livestock.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-09-20
Further Info :

Pubmed ID

36118329

DOI: Digital Object Identifier

PMC9478787

Related Literature

Article Analysis
・Effective treatment of echinacea
SNS
PICO Info
in preparation
Languages

English

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