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Invasive Fungal Disease in Patients with Myeloid Malignancies: A Retrospective Cohort Study of a Diagnostic-Driven Care Pathway Withholding Mould-Active Prophylaxis.
Author: BlijlevensNicole M A, BuilJochem B, De KortElizabeth A, SchaapNicolaas P M, Schaefer-ProkopCornelia, SchalekampSteven, Van der VeldenWalter J F M, VerweijPaul E
Original Abstract of the Article :
Patients receiving remission induction therapy for acute myeloid leukaemia (AML) are at high risk of developing invasive fungal disease (IFD). Newer therapies with targeted antileukemic agents and the emergence of azole resistance pose a challenge to the strategy of primary antifungal prophylaxis. W...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504036/
データ提供:米国国立医学図書館(NLM)
Invasive Fungal Disease: A Silent Threat in Myeloid Malignancies
The world of hematology is often a delicate balance, particularly when dealing with patients undergoing remission induction therapy for acute myeloid leukemia (AML). These patients, already vulnerable to infections, face a silent threat from invasive fungal disease (IFD). This study, like a vigilant desert nomad, examines the challenges associated with managing IFD in this specific patient population. The authors explore the use of a diagnostic-driven care pathway (DCP), a novel approach that relies on culture-directed antifungal prophylaxis. Their findings, like a trail of footprints in the desert, provide valuable insights into the effectiveness of this strategy.
A Diagnostic-Driven Approach: A New Path for Managing Invasive Fungal Disease
The study's findings suggest that the DCP approach, with its focus on culture-directed antifungal prophylaxis, may be a viable alternative to traditional antifungal strategies for managing IFD in patients with AML undergoing remission induction therapy.
Invasive Fungal Disease: A Call for Vigilance
This study, like a desert wind carrying whispers of caution, reminds us of the importance of vigilant monitoring and timely intervention in patients with AML undergoing remission induction therapy. The threat of IFD in this vulnerable population necessitates careful consideration of effective management strategies.
Dr.Camel's Conclusion
Invasive fungal disease, like a hidden scorpion in the sand, can be a silent threat to patients with myeloid malignancies. This study's exploration of a diagnostic-driven care pathway provides a valuable roadmap for navigating this complex terrain.
Date :
- Date Completed n.d.
- Date Revised 2022-09-28
Further Info :
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