Invasive Fungal Disease in Patients with Myeloid Malignancies: A Retrospective Cohort Study of a Diagnostic-Driven Care Pathway Withholding Mould-Active Prophylaxis.

Author: BlijlevensNicole M A, BuilJochem B, De KortElizabeth A, SchaapNicolaas P M, Schaefer-ProkopCornelia, SchalekampSteven, Van der VeldenWalter J F M, VerweijPaul E

Paper Details 
Original Abstract of the Article :
Patients receiving remission induction therapy for acute myeloid leukaemia (AML) are at high risk of developing invasive fungal disease (IFD). Newer therapies with targeted antileukemic agents and the emergence of azole resistance pose a challenge to the strategy of primary antifungal prophylaxis. W...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504036/

データ提供:米国国立医学図書館(NLM)

Invasive Fungal Disease: A Silent Threat in Myeloid Malignancies

The world of hematology is often a delicate balance, particularly when dealing with patients undergoing remission induction therapy for acute myeloid leukemia (AML). These patients, already vulnerable to infections, face a silent threat from invasive fungal disease (IFD). This study, like a vigilant desert nomad, examines the challenges associated with managing IFD in this specific patient population. The authors explore the use of a diagnostic-driven care pathway (DCP), a novel approach that relies on culture-directed antifungal prophylaxis. Their findings, like a trail of footprints in the desert, provide valuable insights into the effectiveness of this strategy.

A Diagnostic-Driven Approach: A New Path for Managing Invasive Fungal Disease

The study's findings suggest that the DCP approach, with its focus on culture-directed antifungal prophylaxis, may be a viable alternative to traditional antifungal strategies for managing IFD in patients with AML undergoing remission induction therapy.

Invasive Fungal Disease: A Call for Vigilance

This study, like a desert wind carrying whispers of caution, reminds us of the importance of vigilant monitoring and timely intervention in patients with AML undergoing remission induction therapy. The threat of IFD in this vulnerable population necessitates careful consideration of effective management strategies.

Dr.Camel's Conclusion

Invasive fungal disease, like a hidden scorpion in the sand, can be a silent threat to patients with myeloid malignancies. This study's exploration of a diagnostic-driven care pathway provides a valuable roadmap for navigating this complex terrain.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-09-28
Further Info :

Pubmed ID

36135650

DOI: Digital Object Identifier

PMC9504036

Related Literature

SNS
PICO Info
in preparation
Languages

English

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