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Psychostimulants Modafinil, Atomoxetine and Guanfacine Impair Bone Cell Differentiation and MSC Migration.
Author: BökerKai O, Di FazioPietro, JäckleKatharina, LehmannWolfgang, SchillingArndt F, WagenerNele, WeiserLukas
Original Abstract of the Article :
Attention deficit hyperactivity disorder (ADHD) is one of the most common worldwide mental disorders in children, young and adults. If left untreated, the disorder can continue into adulthood. The abuse of ADHD-related drugs to improve mental performance for studying, working and everyday life is al...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499654/
データ提供:米国国立医学図書館(NLM)
Cognitive Enhancers and Bone Health: A Potential Link
This study investigates the potential effects of [psychostimulants] commonly used for [attention deficit hyperactivity disorder (ADHD)] on [bone cell differentiation] and [mesenchymal stem cell (MSC) migration]. The authors examined the impact of [modafinil, atomoxetine, and guanfacine] on the ability of [hMSCs] to differentiate into [osteoblasts] and on their [migration capacity]. Their findings suggest that these [psychostimulants] can negatively influence [bone cell differentiation] and [MSC migration], raising concerns about their potential impact on [bone health] in individuals with [ADHD] and those who use these drugs for non-medical purposes.
Cognitive Enhancement and Bone Health: A Balancing Act
This research highlights the potential for [cognitive enhancers] to have unintended effects on [bone health]. The authors demonstrate that [modafinil, atomoxetine, and guanfacine] can disrupt [bone cell differentiation] and [MSC migration], suggesting a potential link between [cognitive enhancement] and [bone health]. This underscores the need for further research to understand the long-term implications of [psychostimulant use] on [bone health].
Navigating the Use of Cognitive Enhancers: An Informed Approach
This study provides valuable insights into the potential [side effects] associated with [cognitive enhancers], highlighting the need for [informed decision-making] regarding their use. The authors emphasize the importance of weighing the potential benefits against the risks, particularly in the context of [long-term health].
Dr.Camel's Conclusion
This research sheds light on the potential impact of [cognitive enhancers] on [bone health], suggesting a need for further investigation into the long-term implications of their use. Just as a camel adapts to the challenges of the desert, individuals taking [cognitive enhancers] should be aware of their potential impact on bone health and consult with healthcare providers to make informed decisions regarding their use.
Date :
- Date Completed 2022-09-26
- Date Revised 2022-09-28
Further Info :
Related Literature
English
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