A Comprehensive Review of Daridorexant, a Dual-Orexin Receptor Antagonist as New Approach for the Treatment of Insomnia.

Author: BiałaGrażyna, GrabowskaKarolina, KurowskaAntonina, ZiemichódWojciech

Paper Details 
Original Abstract of the Article :
Insomnia affects 4.4-4.8% of the world's population, but because the effect of hypnotic drugs is limited and may cause harmful side-effects, scientists are turning their attention to developing drugs that act on the orexin system. Daridorexant, a selective dual-orexin receptor antagonist (DORA), has...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502995/

データ提供:米国国立医学図書館(NLM)

Daridorexant: A New Hope for Insomnia

Insomnia, the inability to sleep, can significantly impact our quality of life. This research explores the potential of daridorexant, a new drug that targets the orexin system, a brain region involved in regulating sleep and wakefulness, as a treatment for insomnia. The study reviews the pharmacodynamics, preclinical and clinical data, pharmacokinetics, and safety profile of daridorexant, highlighting its potential as a novel therapeutic agent for insomnia.

Daridorexant: A New Dawn for Sleep

This research, like a camel finding a cool oasis after a long, arduous journey, offers hope for individuals struggling with insomnia. The study highlights the promising potential of daridorexant, a new medication that targets the orexin system, to effectively treat insomnia without causing significant side effects.

Getting a Good Night's Sleep: A Guide to Restful Nights

If you're struggling with insomnia, it's important to talk to your doctor. They can help you identify the underlying cause of your sleep problems and develop a personalized treatment plan. In addition to medication, there are many lifestyle strategies that can help improve sleep, such as maintaining a regular sleep schedule, creating a relaxing bedtime routine, and avoiding caffeine and alcohol before bed.

Dr. Camel's Conclusion

This research, like a camel navigating a vast and sometimes treacherous desert, sheds light on a new potential treatment for insomnia. The study highlights the promising therapeutic potential of daridorexant, offering a glimmer of hope for individuals struggling with this common sleep disorder.
Date :
  1. Date Completed 2022-09-26
  2. Date Revised 2022-09-28
Further Info :

Pubmed ID

36144776

DOI: Digital Object Identifier

PMC9502995

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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