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[Invasive fungal infections in immunocompromised children in paediatric haematology: Recommendations for management in SFCE centres].

Author: Alby-LaurentFanny, BrethonBenoît, ChahlaWadi Abou, DomenechCarine, DupontDamien, GandemerVirginie, GueguenGwenaelle, LanternierFanny, PasquetMarlène, PhilippeMichael, PluchartClaire

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Practice GuidelineGuidelines and recommendations for the diagnosis and treatment of specific medical conditions in medical practice.

Overview

Invasive fungal infections (IFIs) are a significant threat for children with hematologic malignancies. This article provides specific recommendations for paediatric management of IFIs in hematology, taking into account the unique characteristics and challenges of this patient population.
Paper Details　
Original Abstract of the Article :
To date, invasive fungal infections (IFIs) are still responsible for a high mortality rate in children managed for haematological malignancy. Although Candida and Aspergillus infections remain in the majority, emerging fungal infections are increasingly common. Children differ from adults in their p...See full text at original site
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引用元：
https://doi.org/10.1016/j.bulcan.2022.08.004

データ提供：米国国立医学図書館（NLM）

Invasive Fungal Infections in Immunocompromised Children

This research focuses on the management of invasive fungal infections (IFIs) in immunocompromised children, a critical area of concern in pediatric hematology. The study highlights the unique challenges associated with IFIs in this population, including differences in fungal colonization, pharmacokinetics, and treatment approaches compared to adults.

Fungal Infections in Immunocompromised Children: A Desert of Challenges

The study underscores the high mortality rates associated with IFIs in immunocompromised children, emphasizing the need for effective and timely treatment. It highlights the increasing prevalence of emerging fungal infections, challenging the traditional approach to IFI management. This is like navigating a shifting desert landscape, where new challenges and threats emerge constantly, requiring adaptability and vigilance to maintain a safe and successful journey.

A Multi-faceted Approach to IFI Management

The study emphasizes the importance of a multi-faceted approach to IFI management, taking into account the unique characteristics of each child, the specific fungal pathogen, and the underlying immune compromise. It highlights the need for specific paediatric management recommendations, tailored to the unique needs of this vulnerable population. This is like assembling a caravan for a desert journey, bringing together different skills and resources to overcome the challenges and ensure a successful expedition.

Dr.Camel's Conclusion

This research sheds light on the critical challenges associated with IFIs in immunocompromised children, reminding us of the importance of vigilance and expertise when navigating this complex territory. It's like exploring a hidden canyon within a vast desert, requiring careful observation and a collaborative approach to successfully reach the destination. Continued research and advancements in diagnostic and therapeutic approaches will be essential for improving outcomes and ensuring better care for these vulnerable children.

Date :
  1. Date Completed 2022-10-25
  2. Date Revised 2022-10-25
Further Info :

Pubmed ID

36184333

DOI: Digital Object Identifier

10.1016/j.bulcan.2022.08.004

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