Oral mannitol for bowel preparation: a dose-finding phase II study.

Author: BraviIvana, CarnovaliMarino, CesaroPaola, CiprandiGiorgio, Di PaoloDhanai, ElliLuca, FioriGiancarla, GrazioliLeonardo Minelli, HinkelCarsten, JakobsRalf, ManesGianpiero, PradaAlberto, RadaelliFranco, SoruPietro, SpadaCristiano, TontiniGian Eugenio, UebelPeter, ValatsJean Christophe, VecchiMaurizio, ZimmermannTim

Paper Details 
Original Abstract of the Article :
Successful bowel preparation (BP) for colonoscopy depends on the instructions, diet, the laxative product, and patient adherence, which all affect colonoscopy quality. Nevertheless, there are no laxatives which combine effectiveness, safety, easy self-administration, good patient acceptance, and low...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649514/

データ提供:米国国立医学図書館(NLM)

The Quest for Optimal Bowel Preparation: Mannitol Emerges as a Contender

The world of gastroenterology is always seeking to improve colonoscopy preparation, a crucial step in the diagnosis and treatment of various conditions. This study delves into the potential of mannitol, a sugar alcohol, as a bowel preparation agent. The researchers conducted a dose-finding phase II study to evaluate the efficacy and safety of mannitol in preparing patients for colonoscopy. Their findings suggest that mannitol could be a promising candidate for bowel preparation, offering a potential alternative to existing methods. The study highlights the ongoing search for optimal bowel preparation agents, aiming to improve patient comfort and enhance the quality of colonoscopy procedures. This research underscores the importance of continuous innovation and the pursuit of improved patient care.

Mannitol: A Potential Solution for Bowel Preparation

The study's results indicate that mannitol may be an effective and safe option for bowel preparation. The researchers found that mannitol demonstrated adequate efficacy in preparing patients for colonoscopy. The study suggests that mannitol could be a viable alternative to existing bowel preparation agents, offering potential advantages such as improved patient acceptance and lower cost. The findings provide a strong foundation for further research into the use of mannitol for bowel preparation, exploring its potential benefits in clinical practice. This research is a valuable step in the quest for improved colonoscopy preparation.

A More Comfortable Colonoscopy Experience

The potential of mannitol for bowel preparation holds exciting implications for patient comfort. If mannitol proves to be an effective and well-tolerated bowel preparation agent, it could significantly improve the patient experience during colonoscopy. This research is a promising step toward a more comfortable and efficient colonoscopy procedure, ultimately leading to improved patient care.

Dr.Camel's Conclusion

The search for the perfect bowel preparation agent is like a camel seeking the perfect oasis. This study suggests that mannitol may be a promising oasis in this vast desert, offering a potentially effective and well-tolerated option for preparing patients for colonoscopy. If further research confirms its effectiveness and safety, mannitol could significantly improve the patient experience, making the colonoscopy procedure a little less daunting and a bit more comfortable.

Date :
  1. Date Completed 2022-11-16
  2. Date Revised 2022-11-16
Further Info :

Pubmed ID

36287232

DOI: Digital Object Identifier

PMC9649514

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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