Botulinum toxin type A treatment of four cases of Wilson disease with lower limb dystonia: A prospective study.

Author: CaoZeyu, ChenShangzhi, HanYongsheng, RaoRao, WuTong, XingSaiwei

Paper Details 
Original Abstract of the Article :
Botulinum toxin type A (BoNT-A) has been recommended in various neurological disorders as a useful tool for alleviating dystonia. In Wilson disease (WD) patients with dystonia, BoNT-A injection can be used as a treatment modality when conventional treatment is ineffective for alleviating symptoms. T...See full text at original site
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引用元:
https://doi.org/10.1016/j.toxicon.2022.106959

データ提供:米国国立医学図書館(NLM)

Botulinum Toxin Type A: A Promising Treatment for Lower Limb Dystonia in Wilson Disease

Wilson disease (WD), a rare genetic disorder, can cause dystonia, a movement disorder characterized by involuntary muscle contractions. This study investigated the efficacy of botulinum toxin type A (BoNT-A) injection in treating lower limb dystonia in WD patients. The researchers prospectively evaluated four WD patients with lower limb dystonia who received BoNT-A injections. They assessed the efficacy of injections using clinical scales, surface electromyography (EMG), and gait analysis. The results showed significant improvements in gait parameters, decreased iEMG activity, and improvements in clinical scales, suggesting that BoNT-A injection effectively alleviated symptoms in these patients.

Botulinum Toxin Type A: A Potential Solution for Wilson Disease-Related Dystonia

This study suggests that BoNT-A injection may be a valuable treatment option for WD patients experiencing lower limb dystonia. The effectiveness of BoNT-A in alleviating symptoms provides a potential solution for managing this challenging condition.

Living with Wilson Disease: Managing Symptoms and Maintaining Quality of Life

This research provides valuable information for individuals with WD, highlighting a potential treatment for dystonia. The study encourages patients to discuss treatment options with their healthcare providers to develop personalized strategies for managing symptoms and maintaining quality of life. Early diagnosis and proactive management are crucial for individuals living with WD.

Dr. Camel's Conclusion

This study highlights the potential of BoNT-A injection in treating lower limb dystonia in WD patients, offering a promising therapeutic option for managing this complex condition. The research underscores the importance of exploring innovative treatment approaches for rare diseases to improve the lives of patients.

Date :
  1. Date Completed 2022-12-19
  2. Date Revised 2022-12-21
Further Info :

Pubmed ID

36343759

DOI: Digital Object Identifier

10.1016/j.toxicon.2022.106959

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SNS
PICO Info
in preparation
Languages

English

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