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Spontaneous reporting of adverse reactions related to proton pump inhibitors.

Author: CicalaGiuseppe, CutroneoPaola, DipasqualeValeria, LaganàFrancesca, RomanoClaudio, SpinaEdoardo, TrimarchiGiuseppe

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Most PPI-related ADRs are non-serious. Omeprazole and combination therapy seem to be associated with ADR seriousness.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Proton pump inhibitors (PPIs) are widely prescribed in all age groups, and their use is increasing. However, their safety profile has been frequently questioned. AIMS: The aim of this study was to analyze the characteristics of PPI-related adverse drug reactions (ADRs) reported to the I...See full text at original site
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引用元：
https://doi.org/10.1016/j.dld.2022.10.024

データ提供：米国国立医学図書館（NLM）

Proton Pump Inhibitors: Navigating the Side Effects

Proton pump inhibitors (PPIs) are widely prescribed medications used to reduce stomach acid production. This study analyzes adverse drug reactions (ADRs) reported to the Italian spontaneous reporting system (SRS) database related to PPIs. The study found that while most ADRs were non-serious, omeprazole, a commonly used PPI, was associated with a higher frequency of serious ADRs. This highlights the need for careful monitoring and consideration of potential risks associated with PPI use.

Uncovering the Secrets: ADRs in the Desert of Medication

This study takes a deep dive into the side effects of proton pump inhibitors (PPIs), a crucial medication used to manage stomach acid. It's like exploring a vast desert of medical knowledge, seeking to understand the potential consequences of medication use. The researchers found that while most PPIs are well-tolerated, omeprazole was linked to a higher frequency of serious side effects, urging healthcare providers to exercise caution and carefully monitor patients on this medication.

Staying Safe: A Journey Through the Desert of Medication

This study serves as a reminder to be aware of the potential side effects of medications, even those commonly prescribed. It's like carefully navigating a desert, avoiding hidden dangers and seeking guidance to ensure a safe journey. The researchers emphasize the need for vigilant monitoring and communication with healthcare providers to minimize risks associated with medication use.

Dr. Camel's Conclusion

This study highlights the importance of being aware of the potential side effects of even commonly prescribed medications like proton pump inhibitors. It's like traversing a desert, where unexpected challenges can arise even on familiar paths. By being vigilant and communicating with healthcare providers, we can navigate the desert of medication with greater safety and awareness, ensuring a smoother and healthier journey.

Date :
  1. Date Completed 2023-05-01
  2. Date Revised 2023-07-20
Further Info :

Pubmed ID

36404233

DOI: Digital Object Identifier

10.1016/j.dld.2022.10.024

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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