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Effects of ranolazine on various outcomes in patients with stable angina: an updated meta-analysis.

Author: KallistratosManolis, ManolisAthanasios, PoulimenosLeonidas, ThomopoulosCostas, ZamfirTatiana

Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study determined the effect of ranolazine vs. placebo in angina patients on selective measures of the ischemic burden, cardiovascular outcomes, including atrial fibrillation incidence, in-treatment glycohemoglobin levels, permanent discontinuations because of side effects, and the achieved between-arms blood pressure and heart rate difference.
Paper Details　
Original Abstract of the Article :
We determined the effect of ranolazine vs. placebo in angina patients on 1) selective measures of the ischemic burden, 2) cardiovascular outcomes, including atrial fibrillation incidence, 3) the in-treatment glycohemoglobin levels and the permanent discontinuations because of side effects, and 4) th...See full text at original site
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引用元：
https://doi.org/10.1016/j.hjc.2022.12.002

データ提供：米国国立医学図書館（NLM）

Ranolazine: A Beacon in the Desert of Stable Angina

Stable angina, a condition characterized by chest pain caused by reduced blood flow to the heart, is like a persistent desert wind, causing discomfort and limiting daily activities. This research, a beacon of hope in the desert of stable angina, explores the effects of ranolazine, a medication used to treat angina, on various outcomes in patients with this condition. The study delves into the impact of ranolazine on ischemic burden, cardiovascular outcomes, and the overall well-being of patients.

A Multifaceted Approach

The study reveals that ranolazine, compared to placebo, demonstrates a favorable effect on several measures, including reducing ischemic burden, improving cardiovascular outcomes, and potentially mitigating the risk of atrial fibrillation. While further research is needed to fully understand the benefits of ranolazine, this study offers encouraging findings for patients with stable angina. This research, like a well-stocked oasis, provides valuable information for navigating the complexities of angina management.

Finding Relief in the Desert

This research offers valuable information for patients with stable angina. It highlights the potential benefits of ranolazine in reducing chest pain, improving cardiovascular health, and enhancing overall well-being. However, as with any journey in the desert, it's crucial to consult a healthcare professional to determine the most appropriate treatment approach, considering individual needs and potential side effects. This research serves as a guide, helping patients find relief and navigate the challenges of stable angina.

Dr. Camel's Conclusion

This research, like a sturdy camel carrying a valuable cargo, offers a comprehensive assessment of ranolazine's effects on patients with stable angina. The findings suggest that this medication may offer a multi-faceted approach to managing this condition, improving both ischemic burden and overall cardiovascular health. It's a reminder that even in the arid landscape of chronic disease, there are options available to alleviate symptoms and enhance quality of life.

Date :
  1. Date Completed 2023-05-30
  2. Date Revised 2023-05-30
Further Info :

Pubmed ID

36481415

DOI: Digital Object Identifier

10.1016/j.hjc.2022.12.002

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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