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Clinical and Liver Biochemistry Phenotypes, and Outcome in 133 Patients with Anti-seizure Drug-Induced Liver Injury.

Author: DevarbhaviHarshad, GowdaVinod, KothariKsheetij, KurienSunu Sara, PatilMallikarjun, SinghRajvir, SridharAarthi

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study investigated the clinical and demographic characteristics, the liver injury pattern, the outcome, and the agents responsible for hepatotoxicity in a large cohort of DILI registry patients.
Paper Details　
Original Abstract of the Article :
Anti-seizure drugs that cause idiosyncratic drug-induced liver injury (DILI) are an important cause of morbidity and mortality in individuals exposed to these drugs. The clinical and demographic characteristics, the liver injury pattern, the outcome, and the agents responsible for hepatotoxicity hav...See full text at original site
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引用元：
https://doi.org/10.1007/s10620-022-07777-1

データ提供：米国国立医学図書館（NLM）

Unmasking the Mystery of Drug-Induced Liver Injury

Drug-induced liver injury (DILI) is a serious concern, causing significant morbidity and mortality. This study investigated the clinical and demographic characteristics of patients experiencing DILI, focusing on the specific anti-seizure drugs responsible for the injury. The authors analyzed a large cohort of patients from a DILI registry, identifying patterns in the liver injury and exploring the factors contributing to this adverse event. This study provides valuable insights into the complex world of DILI, helping us to better understand its causes and potential interventions.

Understanding the Clues Behind Drug-Induced Liver Injury

This study is like a detective investigating a complex case, uncovering valuable clues about the underlying causes of DILI. By carefully examining a large number of cases, the authors have revealed patterns and risk factors that could guide future research and clinical practice. This research is an important step toward preventing and managing DILI, protecting patients from this potentially devastating complication.

Safeguarding Your Liver: Considerations for Medication Safety

This research serves as a reminder of the importance of being aware of the potential risks associated with medications. Always talk to your doctor about any medications you are taking, including potential side effects and interactions. It's crucial to be proactive about your health and take steps to mitigate potential risks.

Dr.Camel's Conclusion

This research journey into the desert of DILI highlights the importance of understanding the complex interplay between medications and the human body. By unraveling the mysteries of DILI, we can develop safer and more effective treatments, ensuring the well-being of patients. This study serves as a reminder to be vigilant about our health and seek expert advice when navigating the vast desert of pharmaceuticals.

Date :
  1. Date Completed 2023-04-28
  2. Date Revised 2023-05-12
Further Info :

Pubmed ID

36484972

DOI: Digital Object Identifier

10.1007/s10620-022-07777-1

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Languages

English

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