Paper Details

  1. Home
  2. Paper Details

Clinical predictors of efavirenz-based regimen treatment durability: A two-year case-control study of antiretroviral-naïve patients.

Author: AbidinZarena Zainul, ChidambaramSuresh Kumar, FahrniMathumalar Loganathan, LazzarinoAntonio Ivan, MisranNurul Fatin Laila

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Efavirenz-associated adverse drug events were associated with a significant increase in treatment interruption. Intravenous drug use, opportunistic infections, and serious adverse events were independent predictors of treatment interruption.
Paper Details　
Original Abstract of the Article :
BACKGROUND: While efavirenz-associated adverse drug events (ADEs) were widely established, the clinical relevance is uncertain. OBJECTIVES: We aimed to assess the extent of treatment interruption caused by efavirenz-associated ADEs. METHODS: A case-control study of efavirenz recipients who did, ve...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/j.jiph.2022.12.001

データ提供：米国国立医学図書館（NLM）

Clinical Predictors of Efavirenz-Based Regimen Treatment Durability

Efavirenz, an antiretroviral medication used to treat HIV, is like a desert traveler's water supply, providing essential support but potentially causing side effects. This study examines the factors that influence the duration of treatment with efavirenz-based regimens in HIV-positive individuals. The researchers found that various clinical factors, such as intravenous drug use and opportunistic infections, can significantly impact the durability of treatment with efavirenz, highlighting the need for personalized approaches to medication management in HIV care.

Efavirenz Treatment Durability: Navigating the Desert of HIV Care

This study delves into the complexities of efavirenz treatment in HIV-positive individuals, highlighting the importance of personalized approaches to medication management. The researchers discovered that certain clinical factors can significantly impact the durability of treatment with efavirenz, underscoring the need for careful monitoring and tailored treatment strategies.

Personalized Approaches to HIV Treatment

This study emphasizes the importance of personalized approaches to HIV treatment, recognizing that each individual's journey through the desert of this condition is unique. The researchers provide valuable insights into the factors that influence treatment durability with efavirenz, underscoring the need for individualized care plans and vigilant monitoring of treatment outcomes.

Dr. Camel's Conclusion

This study reveals the importance of individualized care in the desert of HIV treatment. The researchers found that specific factors, such as intravenous drug use and opportunistic infections, can affect the duration of treatment with efavirenz. This research underscores the need for personalized approaches to medication management to optimize outcomes for individuals living with HIV.

Date :
  1. Date Completed 2022-12-20
  2. Date Revised 2022-12-21
Further Info :

Pubmed ID

36508946

DOI: Digital Object Identifier

10.1016/j.jiph.2022.12.001

Related Literature

Article Analysis
・Side Effects of efavirenz
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.