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Antipsychotics and risk of QT prolongation: a pharmacovigilance study.
Author: BordetConstance, GalinierMichel, GarciaPhilippe, MontastrucFrançois, SalvoFrancesco, SommetAgnès, TouafchiaAnthony
Original Abstract of the Article :
While meta-analyses of clinical trials found that lurasidone and partial dopamine agonists (brexpiprazole and aripiprazole) were the antipsychotics less likely to cause QTc prolongation, and sertindole, amisulpride, and ziprasidone were the most frequently associated with this adverse drug reaction;...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1007/s00213-022-06293-4
データ提供:米国国立医学図書館(NLM)
Navigating the Risks of Antipsychotics
Mental health disorders, like depression and schizophrenia, are complex conditions requiring careful management. Antipsychotic medications play a crucial role in treating these disorders, but they can also carry potential risks, including the prolongation of the QT interval on an electrocardiogram (ECG). This study explores the risk of QT prolongation associated with different antipsychotic medications, using real-world data from pharmacovigilance studies.
Understanding the Risks of QT Prolongation
The study highlights the importance of considering the potential risk of QT prolongation when prescribing antipsychotics. It emphasizes that certain medications are more likely to cause this adverse drug reaction than others. The findings provide valuable information for clinicians, enabling them to make informed decisions about medication selection and to monitor patients closely for potential cardiac complications.
Prioritizing Cardiac Safety
This study reinforces the need for vigilant monitoring of patients taking antipsychotic medications, particularly those at higher risk for QT prolongation. It highlights the importance of considering individual patient factors, such as pre-existing heart conditions and other medications, when making prescribing decisions. This research underscores the importance of prioritizing cardiac safety in the treatment of mental health disorders.
Dr.Camel's Conclusion
Just as a camel navigating a desert landscape needs to be mindful of potential dangers, individuals taking antipsychotics require careful monitoring. This study sheds light on the risks associated with QT prolongation, reminding us that medication selection and patient monitoring are crucial for ensuring cardiac safety. It's essential to work closely with healthcare providers to navigate the complexities of mental health treatment and prioritize both mental and physical well-being.
Date :
- Date Completed 2023-01-09
- Date Revised 2023-01-11
Further Info :
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