Paper Details

  1. Home
  2. Paper Details

Successful treatment of switching from benzodiazepine to orexin receptor antagonists improves cognitive function in psychiatric disorders: four case reports.

Author: HoriHikaru

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This report describes four cases where cognitive dysfunction induced by benzodiazepines was improved by switching to orexin receptor antagonists. These findings suggest that switching to orexin receptor antagonists may be an effective strategy for improving cognitive impairment in patients experiencing benzodiazepine-induced cognitive dysfunction.
Paper Details　
Original Abstract of the Article :
Benzodiazepines are used in the treatmentof anxiety and insomnia. On the other hand, they not only have side effects such as drowsiness, poor concentration, and muscle relaxation but also persistent cognitive decline. Even if we try to reduce the dose of these drugs to improve drug-induced cognitive...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/36539372

データ提供：米国国立医学図書館（NLM）

Switching Medications for Improved Cognitive Function

Benzodiazepines, commonly prescribed for anxiety and insomnia, can sometimes lead to cognitive decline, like a fog settling over the desert landscape. This case series explores the potential benefits of switching from benzodiazepines to orexin receptor antagonists, a newer class of medications, in improving cognitive function in patients with psychiatric disorders. This research offers a glimmer of hope for individuals seeking to mitigate the cognitive effects of benzodiazepines.

Investigating the Cognitive Effects of Medication Switches

The case series describes four patients who experienced improved cognitive function after switching from benzodiazepines to orexin receptor antagonists (suvorexant and lemborexant). These findings suggest that this medication switch may offer a potential solution for individuals experiencing cognitive decline associated with benzodiazepine use. This research suggests that this medication switch may offer a potential solution for individuals experiencing cognitive decline associated with benzodiazepine use.

Exploring Alternatives for Cognitive Enhancement

This case series highlights the importance of exploring alternative medication options for patients experiencing cognitive decline associated with benzodiazepine use. Orexin receptor antagonists, with their unique mechanism of action, may offer a potential solution for improving cognitive function. This research opens a new avenue for exploring ways to mitigate the cognitive effects of benzodiazepines and enhance cognitive function in patients with psychiatric disorders.

Dr. Camel's Conclusion

This case series provides a valuable glimpse into the potential benefits of switching from benzodiazepines to orexin receptor antagonists for improving cognitive function in patients with psychiatric disorders. This research is a reminder that the desert of medical knowledge is constantly evolving, with new discoveries and treatment options emerging. This research encourages a more proactive approach to managing the cognitive effects of medications, ensuring optimal patient outcomes.

Date :
  1. Date Completed 2023-04-03
  2. Date Revised 2023-09-26
Further Info :

Pubmed ID

36539372

DOI: Digital Object Identifier

00004850-202305000-00013

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.