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Comparison of Solriamfetol and Modafinil on Arousal and Anxiety-Related Behaviors in Narcoleptic Mice.
Author: NishinoSeiji, SakaiNoriaki
Original Abstract of the Article :
Wake-promoting agents are used for the management of excessive daytime sleepiness caused by narcolepsy. Clinical and preclinical data suggests that solriamfetol, a novel dopamine and norepinephrine reuptake inhibitor, is a promising therapeutic option for excessive daytime sleepiness. We provide the...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121964/
データ提供:米国国立医学図書館(NLM)
The Battle Against Sleepiness: A Tale of Two Wake-Promoting Agents
In the vast expanse of [narcolepsy research], scientists are constantly searching for effective treatments for [excessive daytime sleepiness]. This study compared two wake-promoting agents, [modafinil] and [solriamfetol], in a head-to-head competition, like a duel in the desert under the scorching sun.
The Winner Emerges: Solriamfetol Shows its Might
Both [modafinil] and [solriamfetol] successfully promoted wakefulness in mice, but [solriamfetol] emerged as the victor in terms of anxiety-related behaviors. Unlike [modafinil], which induced anxiety, [solriamfetol] had no such adverse effects, indicating a more desirable profile for patients seeking relief from sleepiness without unwanted side effects.
A Step Towards a Better Night's Sleep: Balancing Wakefulness and Wellbeing
This research sheds light on the potential benefits of [solriamfetol] for treating [narcolepsy]. Its ability to promote wakefulness without inducing anxiety offers a promising avenue for managing sleep disorders, like finding a cool oasis in a scorching desert.
Dr.Camel's Conclusion
This research illuminates the complexities of narcolepsy and the potential of [solriamfetol] as a wake-promoting agent. It's like finding a sturdy camel in a desert storm, offering stability and a sense of security for those battling sleepiness.
Date :
- Date Completed 2023-04-25
- Date Revised 2023-04-27
Further Info :
Related Literature
English
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