Paper Details 
Original Abstract of the Article :
PURPOSE: To describe the effectiveness of leflunomide as adjunctive therapy with anti-tumor necrosis factor (anti-TNF) agents in pediatric patients with uveitis who are not able to tolerate methotrexate. METHODS: A retrospective case series was performed of pediatric patients who were receiving lef...See full text at original site
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引用元:
https://doi.org/10.3928/01913913-20221118-03

データ提供:米国国立医学図書館(NLM)

Leflunomide: A New Path for Pediatric Uveitis

The world of pediatric uveitis is as complex and intricate as a desert oasis, requiring careful attention to each individual's needs. This research explores the potential of leflunomide as an adjunctive therapy for pediatric patients with uveitis who do not tolerate methotrexate. This is like finding a new source of water in a parched land, offering a fresh and potentially effective treatment option.

The researchers, like skilled desert explorers, meticulously reviewed the cases of pediatric patients who were switched from methotrexate to leflunomide in combination with anti-tumor necrosis factor (anti-TNF) agents. Their findings suggest that leflunomide was well tolerated and associated with lower flare rates and steroid-free remission, offering hope for a more effective and manageable treatment for this challenging condition.

The study highlights the importance of finding alternative treatment options for pediatric patients with uveitis who do not tolerate conventional therapies. It underscores the need for continued research to expand the therapeutic arsenal for this complex condition.

A New Oasis of Hope

This research provides a glimmer of hope for pediatric patients with uveitis who do not tolerate conventional therapies, offering a potentially effective and well-tolerated treatment option.

Dr. Camel's Conclusion

This research is a testament to the ongoing efforts of researchers to find effective treatments for pediatric uveitis. It's a reminder that the search for better health is a journey of exploration and innovation, much like a camel traversing a vast and unpredictable desert landscape.

Date :
  1. Date Completed 2023-12-01
  2. Date Revised 2023-12-01
Further Info :

Pubmed ID

36546781

DOI: Digital Object Identifier

10.3928/01913913-20221118-03

Related Literature

SNS
PICO Info
in preparation
Languages

English

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