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The Effect of Leflunomide as Adjunctive Therapy With a TNF Inhibitor in Pediatric Patients With Uveitis.
Author: CohenEzra, GargNeha, LaMattinaKara C, TsuiEdmund
Original Abstract of the Article :
PURPOSE: To describe the effectiveness of leflunomide as adjunctive therapy with anti-tumor necrosis factor (anti-TNF) agents in pediatric patients with uveitis who are not able to tolerate methotrexate. METHODS: A retrospective case series was performed of pediatric patients who were receiving lef...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.3928/01913913-20221118-03
データ提供:米国国立医学図書館(NLM)
Leflunomide: A New Path for Pediatric Uveitis
The world of pediatric uveitis is as complex and intricate as a desert oasis, requiring careful attention to each individual's needs. This research explores the potential of leflunomide as an adjunctive therapy for pediatric patients with uveitis who do not tolerate methotrexate. This is like finding a new source of water in a parched land, offering a fresh and potentially effective treatment option.
The researchers, like skilled desert explorers, meticulously reviewed the cases of pediatric patients who were switched from methotrexate to leflunomide in combination with anti-tumor necrosis factor (anti-TNF) agents. Their findings suggest that leflunomide was well tolerated and associated with lower flare rates and steroid-free remission, offering hope for a more effective and manageable treatment for this challenging condition.
The study highlights the importance of finding alternative treatment options for pediatric patients with uveitis who do not tolerate conventional therapies. It underscores the need for continued research to expand the therapeutic arsenal for this complex condition.
A New Oasis of Hope
This research provides a glimmer of hope for pediatric patients with uveitis who do not tolerate conventional therapies, offering a potentially effective and well-tolerated treatment option.
Dr. Camel's Conclusion
This research is a testament to the ongoing efforts of researchers to find effective treatments for pediatric uveitis. It's a reminder that the search for better health is a journey of exploration and innovation, much like a camel traversing a vast and unpredictable desert landscape.
Date :
- Date Completed 2023-12-01
- Date Revised 2023-12-01
Further Info :
Related Literature
English
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