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Synthetic Imidazopyridine-Based Derivatives as Potential Inhibitors against Multi-Drug Resistant Bacterial Infections: A Review.

Author: AshamesAkram, BhandareRichie R, SanapalliBharat Kumar Reddy, ShaikAfzal B, SigalapalliDilep Kumar, YeleVidyasrilekha

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Imidazopyridines (IZPs) are fused heterocyclic compounds with diverse pharmacological properties, including antibacterial activity. This review highlights the synthetic strategies for preparing IZPs, focusing on their antibacterial profiles and structure-activity relationships (SAR). The research aims to guide the development of novel, potent antibacterial agents with fewer side effects.
Paper Details　
Original Abstract of the Article :
Fused pyridines are reported to display various pharmacological activities, such as antipyretic, analgesic, antiprotozoal, antibacterial, antitumor, antifungal, anti-inflammatory, and antiapoptotic. They are widely used in the field of medicinal chemistry. Imidazopyridines (IZPs) are crucial classes...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774741/

データ提供：米国国立医学図書館（NLM）

Fighting Multi-Drug Resistant Bacteria: A New Frontier in Antibiotic Research

The rise of multi-drug resistant bacteria is a major threat to global health. This study explores the potential of imidazopyridine derivatives as a new class of antibiotics to combat these resistant strains. It's like a camel searching for a new oasis in a parched desert, seeking out a fresh source of water to combat the effects of drought.

Imidazopyridine Derivatives: A Promising New Weapon Against Resistant Bacteria

This study highlights the potential of imidazopyridine derivatives as a new class of antibiotics. These derivatives show promising antibacterial activity against multi-drug resistant strains, offering hope for new treatments to combat this growing threat.

Antibiotic Research: A Crucial Front in the Fight Against Disease

This study underscores the importance of continued research into new antibiotics to address the growing threat of resistant bacteria. It's a reminder that we must stay ahead of the curve in the fight against infectious diseases.

Dr.Camel's Conclusion

Just as a camel navigates a changing desert landscape, researchers are navigating the ever-evolving world of antibiotic resistance. This study offers a potential new oasis, highlighting the promising potential of imidazopyridine derivatives in the fight against these resistant strains.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-12-25
Further Info :

Pubmed ID

36551338

DOI: Digital Object Identifier

PMC9774741

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Languages

English

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