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Role of primary aging hallmarks in Alzheimer´s disease.

Author: HuaiJisen, ZhaoJin

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Alzheimer's disease (AD) is a debilitating neurodegenerative disease associated with aging. This review explores the role of primary aging hallmarks, such as genomic instability and epigenetic changes, in the development of AD. Understanding these mechanisms could lead to new strategies for preventing or treating AD.
Paper Details　
Original Abstract of the Article :
Alzheimer's disease (AD) is the most common neurodegenerative disease, which severely threatens the health of the elderly and causes significant economic and social burdens. The causes of AD are complex and include heritable but mostly aging-related factors. The primary aging hallmarks include genom...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800733/

データ提供：米国国立医学図書館（NLM）

Unraveling the Mysteries of Alzheimer's Disease: A Look at the Role of Primary Aging Hallmarks

The field of [Alzheimer's disease] (AD) is a complex and challenging one, and the search for effective treatments continues. This study focuses on the role of [primary aging hallmarks] in the development of [AD]. The authors explore the possible mechanisms by which these hallmarks, including [genomic instability], [telomere wear], [epigenetic changes], and [loss of protein stability], contribute to the development of [AD].

Understanding the Roots: The Role of Primary Aging Hallmarks in AD

Imagine the body as a vast and intricate desert: [primary aging hallmarks] are like the shifting sands that gradually erode and change the landscape over time. This study investigates how these changes, which are part of the natural aging process, can contribute to the development of [AD]. Understanding these underlying mechanisms is essential for developing effective treatments and prevention strategies.

A Desert of Complexity: The Need for Further Research

This study sheds light on the intricate relationship between [aging] and [AD], highlighting the need for further research to understand the precise mechanisms involved. It's a reminder that the desert of [neurodegenerative disease] is vast and complex, and we need to continue exploring its hidden pathways to find effective solutions.

Dr. Camel's Conclusion

This study delves into the complex world of [Alzheimer's disease] and its relationship to [primary aging hallmarks]. Understanding these intricate connections is crucial for developing effective strategies to combat this devastating disease. It's a reminder that the journey to understanding [AD] is long and winding, and we need to continue our exploration with patience and persistence.

Date :
  1. Date Completed 2023-01-04
  2. Date Revised 2023-03-28
Further Info :

Pubmed ID

36593969

DOI: Digital Object Identifier

PMC9800733

Related Literature

Article Analysis
・Causes of alzheimer's disease
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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