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Immune checkpoint inhibitor-related myositis: from pathophysiology to treatment.
Author: BhaiSalman, DimachkieMazen M, SundarrajanChandrasekhar
Original Abstract of the Article :
With rapid advances in immuno-oncology, immune checkpoint inhibitors (ICIs) are increasingly used for a broad array of malignancies. This has led to a novel spectrum of adverse effects including ICI-related myositis, a potentially life-threatening neuromuscular complication that must be diagnosed an...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.55563/clinexprheumatol/q7mdjs
データ提供:米国国立医学図書館(NLM)
Navigating the Complexities of Immune Checkpoint Inhibitor-Related Myositis
The field of immuno-oncology has witnessed significant advancements, with immune checkpoint inhibitors (ICIs) revolutionizing cancer treatment. While ICIs offer tremendous promise, they can also lead to a range of adverse effects, including ICI-related myositis, a potentially life-threatening neuromuscular complication. This study delves into the pathophysiology, epidemiology, clinical features, workup, and management of ICI-related myositis, highlighting the critical need for timely diagnosis and treatment.
The study emphasizes the challenges posed by the rarity of ICI-related myositis and the lack of evidence-based guidelines. The researchers call for a collaborative effort to synthesize existing knowledge and advance research in this area to improve patient care.
ICI-Related Myositis: A Complex and Emerging Challenge
This study sheds light on the complexities of ICI-related myositis, a potentially serious complication of cancer immunotherapy. The study highlights the need for heightened awareness of this condition among healthcare professionals and for the development of evidence-based guidelines to guide diagnosis and treatment.
Understanding the Balancing Act of Cancer Treatment
Just as a camel navigating a desert must find a balance between hydration and conserving energy, cancer treatment requires a delicate balance between achieving therapeutic efficacy and managing potential adverse effects. This study highlights the importance of understanding the potential complications associated with new treatments and developing strategies to address them.
Dr.Camel's Conclusion
This comprehensive review of ICI-related myositis provides valuable insights into the pathophysiology, clinical features, and management of this potentially life-threatening complication of cancer immunotherapy. The study underscores the need for continued research and development of evidence-based guidelines to ensure optimal patient care in this emerging field.
Date :
- Date Completed 2023-03-03
- Date Revised 2023-03-03
Further Info :
Related Literature
English
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