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Efficacy of 48 hours dose of phenytoin in prevention of early post-traumatic seizure.

Author: AdeleyeAmos O, AdeoluAugustine A, BadejoOluwakemi A, BalogunJames A, MalomoAdefolarin O, OyemoladeToyin Ayofe, ShokunbiMatthew T

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study investigates the efficacy of a short-course (48-hour dose) of phenytoin in preventing early post-traumatic seizures. Phenytoin has been shown to reduce the incidence of early post-traumatic seizures in some studies, but concerns exist regarding its side effects. The study aims to evaluate the effectiveness of a short-term dose of phenytoin in minimizing these risks.
Paper Details　
Original Abstract of the Article :
Antiseizure medications, such as phenytoin sodium, have been shown in some reports to reduce the incidence of early post-traumatic seizure. These medications, however, are not without side effects which may be dose related or duration related. The risks associated with short-term therapy are minimal...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835875/

データ提供：米国国立医学図書館（NLM）

Short-Term Phenytoin: A Potential Prophylactic Strategy for Post-Traumatic Seizures

Post-traumatic seizures, like a sudden sandstorm, can occur after traumatic brain injuries, adding another layer of complexity to an already challenging situation. This study, like a well-prepared caravan navigating a challenging terrain, investigates the efficacy of short-term phenytoin in preventing these seizures.

Phenytoin: A Potential Prophylactic for Post-Traumatic Seizures

Researchers, like skilled engineers designing a protective barrier, are conducting a study to determine the effectiveness of a 48-hour dose of phenytoin in preventing early post-traumatic seizures. The study aims to balance the potential benefits of reducing seizure incidence with the risks associated with medication use.

Navigating the Complexities of Traumatic Brain Injury: A Balanced Approach

This research, like a desert traveler carefully navigating a challenging path, highlights the importance of a balanced approach to managing post-traumatic seizures. The study's findings could provide valuable insights into the potential benefits and risks of short-term phenytoin therapy, helping clinicians make informed decisions about patient care.

Dr. Camel's Conclusion

This study is an important step towards finding more effective and safe strategies for preventing post-traumatic seizures. By exploring the efficacy of short-term phenytoin, the study could lead to improved management of traumatic brain injury and better outcomes for patients.
Date :
  1. Date Completed n.d.
  2. Date Revised 2023-01-17
Further Info :

Pubmed ID

36644000

DOI: Digital Object Identifier

PMC9835875

Related Literature

Article Analysis
・Side Effects of phenytoin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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