Paper Details
- Home
- Paper Details
An Exemestane Derivative, Oxymestane-D1, as a New Multi-Target Steroidal Aromatase Inhibitor for Estrogen Receptor-Positive (ER<sup>+</sup>) Breast Cancer: Effects on Sensitive and Resistant Cell Lines.
Author: AlmeidaCristina Ferreira, AmaralCristina, Correia-da-SilvaGeorgina, RoleiraFernanda M F, Tavares-da-SilvaElisiário, TeixeiraNatércia, ValenteMaria João, VarelaCarla, VinggaardAnne Marie
Original Abstract of the Article :
Around 70-85% of all breast cancer (BC) cases are estrogen receptor-positive (ER<sup>+</sup>). The third generation of aromatase inhibitors (AIs) is the first-line treatment option for these tumors. Despite their therapeutic success, they induce several side effects and resistance, which limits thei...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865664/
データ提供:米国国立医学図書館(NLM)
A New Multi-Target Steroidal Aromatase Inhibitor for Breast Cancer
This study investigates the potential of a novel exemestane derivative, Oxymestane-D1, as a multi-target drug for the treatment of estrogen receptor-positive (ER+) breast cancer. The study explores the compound's effects on both sensitive and resistant breast cancer cell lines, focusing on its ability to inhibit aromatase activity, modulate estrogen receptor activity, and induce apoptosis. The study's findings suggest that Oxymestane-D1 may be a promising new treatment option for ER+ breast cancer, potentially overcoming the challenges of resistance and side effects associated with current therapies.
A New Frontier in Breast Cancer Treatment
This study highlights the potential of a new multi-target drug, Oxymestane-D1, to address the challenges of ER+ breast cancer treatment. The study's findings suggest that this compound may offer a more effective and well-tolerated approach to managing this complex disease.
Hope for Individuals with Breast Cancer
This research offers hope for individuals diagnosed with ER+ breast cancer, presenting a potential new treatment option with the ability to overcome resistance and minimize side effects. The study's findings underscore the importance of ongoing research to develop new and improved therapies for breast cancer, offering a path to a brighter future for those living with this disease. Just as a camel adapts to the challenges of the desert by utilizing its unique physical adaptations, researchers are adapting their approaches to cancer treatment by developing innovative and multi-targeted therapies.
Dr. Camel's Conclusion
This study is a testament to the power of scientific innovation in the fight against breast cancer. The potential of Oxymestane-D1 to overcome the challenges of resistance and side effects offers a beacon of hope for a more effective and well-tolerated treatment approach. We must continue to invest in research and development to find even better treatments for breast cancer, just as a camel seeks out the most abundant and nourishing oases in the desert.
Date :
- Date Completed 2023-01-24
- Date Revised 2023-01-24
Further Info :
Related Literature
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.