Real world use of dolutegravir two drug regimens.

Author: AkoduJane, AmbroseAlissa, BarberTristan J, BowmanConor, FloresKatia, HartJennifer, HunterAlan, KanitkarTanmay, SimoesPedro

Paper Details 
Original Abstract of the Article :
BACKGROUND: Since 2015, we prescribed dolutegravir (DTG)-based two drug regimens (DTG-2DR) for 620 people [total cohort 3133 (19.8%)]. METHOD: Clinic database search 1 January 15 to 31 October 21. Demographic, tolerability and HIV related data analysed. RESULTS: In total, 620 people identified; 56...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/36728219

データ提供:米国国立医学図書館(NLM)

Dolutegravir-Based Two-Drug Regimens: A Real-World Perspective

This study examines the real-world use of dolutegravir (DTG)-based two-drug regimens (DTG-2DR) for the treatment of HIV infection. The researchers analyzed data from a large cohort of patients who initiated or switched to DTG-2DR, providing valuable insights into the effectiveness and tolerability of these regimens in clinical practice.

DTG-2DR: A Promising Option for HIV Treatment

The study's findings indicate that DTG-2DRs demonstrate high efficacy in a real-world setting, with a majority of patients achieving viral suppression. The study also highlights the importance of adherence to therapy and the potential for resistance development, particularly with multi-tablet regimens. The findings provide important information for clinicians making treatment decisions for HIV-infected patients.

Optimizing HIV Treatment: Balancing Efficacy and Tolerability

This research highlights the ongoing efforts to optimize HIV treatment strategies, balancing efficacy with tolerability and minimizing the risk of resistance development. The study's findings underscore the importance of selecting appropriate regimens based on individual patient factors and carefully monitoring treatment response. The findings provide valuable information for clinicians seeking to provide the best possible care for their HIV-infected patients.

Dr.Camel's Conclusion

This study, like a camel caravan navigating a vast desert, highlights the ongoing journey to improve HIV treatment. The findings suggest that DTG-2DRs are a promising option for many patients, but careful monitoring and adherence to therapy are crucial for achieving long-term success. This research underscores the importance of collaboration between clinicians, researchers, and patients in the quest to control HIV infection and improve the lives of those affected by this disease.

Date :
  1. Date Completed 2023-03-16
  2. Date Revised 2023-05-23
Further Info :

Pubmed ID

36728219

DOI: Digital Object Identifier

00002030-202304010-00010

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English

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