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Real world use of dolutegravir two drug regimens.
Author: AkoduJane, AmbroseAlissa, BarberTristan J, BowmanConor, FloresKatia, HartJennifer, HunterAlan, KanitkarTanmay, SimoesPedro
Original Abstract of the Article :
BACKGROUND: Since 2015, we prescribed dolutegravir (DTG)-based two drug regimens (DTG-2DR) for 620 people [total cohort 3133 (19.8%)]. METHOD: Clinic database search 1 January 15 to 31 October 21. Demographic, tolerability and HIV related data analysed. RESULTS: In total, 620 people identified; 56...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/36728219
データ提供:米国国立医学図書館(NLM)
Dolutegravir-Based Two-Drug Regimens: A Real-World Perspective
This study examines the real-world use of dolutegravir (DTG)-based two-drug regimens (DTG-2DR) for the treatment of HIV infection. The researchers analyzed data from a large cohort of patients who initiated or switched to DTG-2DR, providing valuable insights into the effectiveness and tolerability of these regimens in clinical practice.
DTG-2DR: A Promising Option for HIV Treatment
The study's findings indicate that DTG-2DRs demonstrate high efficacy in a real-world setting, with a majority of patients achieving viral suppression. The study also highlights the importance of adherence to therapy and the potential for resistance development, particularly with multi-tablet regimens. The findings provide important information for clinicians making treatment decisions for HIV-infected patients.
Optimizing HIV Treatment: Balancing Efficacy and Tolerability
This research highlights the ongoing efforts to optimize HIV treatment strategies, balancing efficacy with tolerability and minimizing the risk of resistance development. The study's findings underscore the importance of selecting appropriate regimens based on individual patient factors and carefully monitoring treatment response. The findings provide valuable information for clinicians seeking to provide the best possible care for their HIV-infected patients.
Dr.Camel's Conclusion
This study, like a camel caravan navigating a vast desert, highlights the ongoing journey to improve HIV treatment. The findings suggest that DTG-2DRs are a promising option for many patients, but careful monitoring and adherence to therapy are crucial for achieving long-term success. This research underscores the importance of collaboration between clinicians, researchers, and patients in the quest to control HIV infection and improve the lives of those affected by this disease.
Date :
- Date Completed 2023-03-16
- Date Revised 2023-05-23
Further Info :
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English
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