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Doravirine Exposure Decreased by Dialysis in a HIV Patient: A Grand Round.
Author: CoddeCyrielle, FaucherJean-François, FromageYeleen, LabriffeMarc, LêMinh P, MonchaudCaroline, WoillardJean-Baptiste
Original Abstract of the Article :
The authors report the case of a 66-year-old male patient who was hemodialyzed 3 times per week for chronic renal failure and treated with 100 mg of doravirine once daily in combination with dolutegravir for HIV-1. No dose adjustment is required for doravirine in cases of severe renal injury, but th...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/36728229
データ提供:米国国立医学図書館(NLM)
The Influence of Dialysis on Doravirine Exposure: A Case Study
The human body is a delicate ecosystem, and when its equilibrium is disrupted, as in the case of chronic renal failure, it requires careful intervention. This case report, published in the journal *[Journal Name]*, explores the impact of dialysis on the exposure of doravirine, a medication used to treat HIV-1. The study investigates a specific case of a patient undergoing hemodialysis, a process similar to a desert oasis providing vital support to the body. The report serves as a case study, providing valuable insights into the interplay between dialysis and medication efficacy.
A Vital Insight into Medication Management
The case report reveals the need for further exploration into the relationship between dialysis and doravirine exposure. While the study underscores the importance of understanding how medical treatments interact with other medical interventions, it does not provide definitive answers regarding dose adjustments or long-term effects.
Navigating the Complexities of Treatment
This case study highlights the complexity of managing chronic conditions. It underscores the need for careful monitoring and individualized approaches to ensure optimal treatment outcomes. As we continue to explore the intricacies of medical interventions, we gain a deeper understanding of the human body's delicate balance.
Dr. Camel's Conclusion
Just as the desert's ecosystem is a delicate balance of life and resilience, so too is the human body. This study underscores the importance of understanding how medical interventions impact each other, allowing us to provide more precise and effective care for our patients.
Date :
- Date Completed 2023-03-20
- Date Revised 2023-08-14
Further Info :
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