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Metronidazole-induced encephalopathy delayed diagnosis due to cerebellar infarction: A case report.
Author: ChaSangha, ChoKang Hee, LeeByung Chan, MoonChang-Won
Original Abstract of the Article :
RATIONALE: Metronidazole is a 5-nitroimidazole antibiotic effective against anaerobic bacterial and parasitic infections. Long-term use may cause side effects in the central nervous system, although the occurrence of encephalopathy is rare. PATIENT CONCERNS: A 73-year-old man was diagnosed with acu...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902015/
データ提供:米国国立医学図書館(NLM)
Metronidazole-Induced Encephalopathy: A Rare Side Effect
The field of neurology is vast and often presents challenging cases. This study focuses on a specific neurological complication, metronidazole-induced encephalopathy, a rare side effect of this commonly used antibiotic. The study employs a case report approach, delving into the detailed clinical presentation and management of a patient who developed this condition. The authors highlight the importance of considering this potential complication, especially in cases of prolonged metronidazole use.
Prolonged Metronidazole Use Can Lead to Neurological Complications
The case study demonstrates that metronidazole, even when used for a long time, can lead to neurological complications, such as encephalopathy and cerebellar infarction. The patient in this study exhibited cognitive decline and gait disturbance after prolonged metronidazole treatment, ultimately requiring discontinuation of the medication. The study underscores the significance of continuous monitoring for neurological changes in patients undergoing long-term metronidazole therapy.
Be Vigilant When Using Metronidazole for Extended Periods
It is crucial for doctors to be aware of the potential for metronidazole to cause encephalopathy, especially with prolonged use. Recognizing this potential side effect can lead to prompt discontinuation of the medication and ultimately minimize the risk of neurological complications. Doctors should keep a watchful eye on patients undergoing prolonged metronidazole therapy to identify any signs of cognitive or neurological changes.
Dr. Camel's Conclusion
Just like a camel navigating the vast desert, doctors must be prepared for unexpected challenges. Metronidazole, while a valuable tool in combating bacterial infections, has the potential to cause neurological complications. The study serves as a reminder to always be vigilant about the potential side effects of medications, especially when used for extended periods. Early detection and prompt intervention are key to ensuring the best possible outcome for patients.
Date :
- Date Completed 2023-02-09
- Date Revised 2023-02-09
Further Info :
Related Literature
English
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