Metronidazole-induced encephalopathy delayed diagnosis due to cerebellar infarction: A case report.

Author: ChaSangha, ChoKang Hee, LeeByung Chan, MoonChang-Won

Paper Details 
Original Abstract of the Article :
RATIONALE: Metronidazole is a 5-nitroimidazole antibiotic effective against anaerobic bacterial and parasitic infections. Long-term use may cause side effects in the central nervous system, although the occurrence of encephalopathy is rare. PATIENT CONCERNS: A 73-year-old man was diagnosed with acu...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902015/

データ提供:米国国立医学図書館(NLM)

Metronidazole-Induced Encephalopathy: A Rare Side Effect

The field of neurology is vast and often presents challenging cases. This study focuses on a specific neurological complication, metronidazole-induced encephalopathy, a rare side effect of this commonly used antibiotic. The study employs a case report approach, delving into the detailed clinical presentation and management of a patient who developed this condition. The authors highlight the importance of considering this potential complication, especially in cases of prolonged metronidazole use.

Prolonged Metronidazole Use Can Lead to Neurological Complications

The case study demonstrates that metronidazole, even when used for a long time, can lead to neurological complications, such as encephalopathy and cerebellar infarction. The patient in this study exhibited cognitive decline and gait disturbance after prolonged metronidazole treatment, ultimately requiring discontinuation of the medication. The study underscores the significance of continuous monitoring for neurological changes in patients undergoing long-term metronidazole therapy.

Be Vigilant When Using Metronidazole for Extended Periods

It is crucial for doctors to be aware of the potential for metronidazole to cause encephalopathy, especially with prolonged use. Recognizing this potential side effect can lead to prompt discontinuation of the medication and ultimately minimize the risk of neurological complications. Doctors should keep a watchful eye on patients undergoing prolonged metronidazole therapy to identify any signs of cognitive or neurological changes.

Dr. Camel's Conclusion

Just like a camel navigating the vast desert, doctors must be prepared for unexpected challenges. Metronidazole, while a valuable tool in combating bacterial infections, has the potential to cause neurological complications. The study serves as a reminder to always be vigilant about the potential side effects of medications, especially when used for extended periods. Early detection and prompt intervention are key to ensuring the best possible outcome for patients.

Date :
  1. Date Completed 2023-02-09
  2. Date Revised 2023-02-09
Further Info :

Pubmed ID

36749268

DOI: Digital Object Identifier

PMC9902015

Related Literature

SNS
PICO Info
in preparation
Languages

English

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