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Effects of Ketanserin, M100907 and Olanzapine on hallucinogenic like action induced by 2,5-dimethoxy-4-methylamphetamine.
Author: LiKaixi, LiuXiaoyan, SuRuibin, ZhangMei
Original Abstract of the Article :
2,5-dimethoxy-4-methylamphetamine (DOM) is a kind of hallucinogen of phenylalkylamine. Psychedelic effects mainly include audiovisual synesthesia, complex imagery, disembodiment etc. that can impair control and cognition leading to adverse consequences such as suicide. By now, there are no specific ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/36752335
データ提供:米国国立医学図書館(NLM)
Hallucinogens: A Journey Through the Desert of Perception
The world of perception, like a vast and enigmatic desert, is full of intricate pathways and unexpected experiences. Hallucinogens, substances that can alter perception and consciousness, can lead us on a journey through this surreal landscape, sometimes with unpredictable and potentially dangerous consequences. This study, like a cautious explorer, investigates the effects of hallucinogens and potential treatments for their adverse effects.
The researchers, like skilled chemists, delved into the effects of 2,5-dimethoxy-4-methylamphetamine (DOM), a hallucinogen, and its impact on the brain. They sought to understand the mechanisms behind DOM's effects and identify potential therapeutic agents to counter its hallucinogenic properties.
Hallucinogens: A Tricky Terrain in the Desert of Perception
The study found that DOM, like a shifting sand dune, can alter perception and induce hallucination-like behavior. The researchers, like experienced guides, tested the effects of three 5-HT2A receptor antagonists: ketanserin, M100907, and olanzapine, seeking to find ways to navigate the challenging terrain of hallucinogenic effects.
Navigating the Desert of Hallucination: A Search for Effective Treatment
This study, like a map leading to a hidden oasis, provides insights into potential treatments for hallucinogenic effects. The researchers, like skilled healers, identified that M100907 showed promising results in reducing hallucinogenic-like behaviors in mice. These findings suggest a possible path toward developing effective treatments for those experiencing hallucinogenic effects.
Dr. Camel's Conclusion
The desert of perception can be a disorienting and unpredictable place, and hallucinogens can lead us on a challenging and potentially dangerous journey. This study, like a compass in the night, provides valuable insights into the effects of hallucinogens and potential treatment strategies. Let's continue to explore this intricate terrain, seeking to understand the complex interplay between mind, body, and perception.
Date :
- Date Completed 2023-03-13
- Date Revised 2023-12-13
Further Info :
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