Real-world treatment of pediatric narcolepsy with pitolisant: A retrospective, multicenter study.

Author: KallweitUlf, LecendreuxMichel, LieberichLea, Pech de LaclauseAnna, PizzaFabio, PlazziGiuseppe, RezaeiRana, TrillerAnnika, VandiStefano

Paper Details 
Original Abstract of the Article :
First symptoms of narcolepsy mostly present during childhood. Pharmacological management options in children are limited, also due to approval status. Pitolisant is an inverse histamine 3 receptor agonist and has been approved for the treatment of adult narcolepsy with or without cataplexy by EMA an...See full text at original site
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引用元:
https://doi.org/10.1016/j.sleep.2023.01.015

データ提供:米国国立医学図書館(NLM)

Pitolisant for Pediatric Narcolepsy: A Real-World Exploration

The world of [pediatric narcolepsy] is often a realm of uncertainty, as the condition can significantly impact a child's life. This study, like a careful guide leading through a challenging terrain, explores the use of [pitolisant] in the real-world setting of children and adolescents with [narcolepsy]. Researchers analyzed the effectiveness and tolerability of this medication in a [retrospective, multicenter study].

A Light in the Darkness for Young Patients

The findings offer a glimmer of hope for patients with [pediatric narcolepsy], as [pitolisant] demonstrated a beneficial effect in managing the condition. The study highlights the potential of this medication in improving the quality of life of young patients, particularly those struggling with [excessive daytime sleepiness and cataplexy].

Navigating the World of Narcolepsy

This study underscores the need for more research on the use of [pitolisant] in [pediatric narcolepsy]. While the real-world data offer encouraging results, further investigation is required to establish its long-term safety and efficacy. Navigating the world of narcolepsy requires a collaborative effort between healthcare professionals and researchers to develop effective and safe treatment options.

Dr. Camel's Conclusion

This study is a reminder that there is hope for children and adolescents living with narcolepsy. Pitolisant shows promise as a treatment option, offering potential relief from the debilitating symptoms of this condition. Further research is crucial to optimize its use and ensure its long-term safety and effectiveness.

Date :
  1. Date Completed 2023-03-13
  2. Date Revised 2023-03-30
Further Info :

Pubmed ID

36758348

DOI: Digital Object Identifier

10.1016/j.sleep.2023.01.015

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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