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Real-world treatment of pediatric narcolepsy with pitolisant: A retrospective, multicenter study.
Author: KallweitUlf, LecendreuxMichel, LieberichLea, Pech de LaclauseAnna, PizzaFabio, PlazziGiuseppe, RezaeiRana, TrillerAnnika, VandiStefano
Original Abstract of the Article :
First symptoms of narcolepsy mostly present during childhood. Pharmacological management options in children are limited, also due to approval status. Pitolisant is an inverse histamine 3 receptor agonist and has been approved for the treatment of adult narcolepsy with or without cataplexy by EMA an...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.sleep.2023.01.015
データ提供:米国国立医学図書館(NLM)
Pitolisant for Pediatric Narcolepsy: A Real-World Exploration
The world of [pediatric narcolepsy] is often a realm of uncertainty, as the condition can significantly impact a child's life. This study, like a careful guide leading through a challenging terrain, explores the use of [pitolisant] in the real-world setting of children and adolescents with [narcolepsy]. Researchers analyzed the effectiveness and tolerability of this medication in a [retrospective, multicenter study].
A Light in the Darkness for Young Patients
The findings offer a glimmer of hope for patients with [pediatric narcolepsy], as [pitolisant] demonstrated a beneficial effect in managing the condition. The study highlights the potential of this medication in improving the quality of life of young patients, particularly those struggling with [excessive daytime sleepiness and cataplexy].
Navigating the World of Narcolepsy
This study underscores the need for more research on the use of [pitolisant] in [pediatric narcolepsy]. While the real-world data offer encouraging results, further investigation is required to establish its long-term safety and efficacy. Navigating the world of narcolepsy requires a collaborative effort between healthcare professionals and researchers to develop effective and safe treatment options.
Dr. Camel's Conclusion
This study is a reminder that there is hope for children and adolescents living with narcolepsy. Pitolisant shows promise as a treatment option, offering potential relief from the debilitating symptoms of this condition. Further research is crucial to optimize its use and ensure its long-term safety and effectiveness.
Date :
- Date Completed 2023-03-13
- Date Revised 2023-03-30
Further Info :
Related Literature
English
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