Safety and tolerability of monoclonal antibodies targeting the CGRP pathway and gepants in migraine prevention: A systematic review and network meta-analysis.

Author: DienerHans-Christoph, HaghdoostFaraidoon, HuesslerEva-Maria, LebedevaElena R, MessinaRoberta, PuleddaFrancesca

Paper Details 
Original Abstract of the Article :
Direct comparisons of the tolerability and safety of migraine preventive treatments targeting the calcitonin gene-related peptide pathway are lacking. This study aimed to compare the safety and tolerability of anti-calcitonin gene-related peptide monoclonal antibodies and gepants in migraine prevent...See full text at original site
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引用元:
https://doi.org/10.1177/03331024231152169

データ提供:米国国立医学図書館(NLM)

Navigating the Desert of Migraine: A Comparative Study of CGRP Pathway Treatments

The desert of [migraine] can be a painful and debilitating experience. This research embarks on a journey to compare the safety and tolerability of different treatments targeting the [calcitonin gene-related peptide (CGRP) pathway] for [migraine prevention]. The researchers, like camel caravan explorers, are searching for the safest and most effective route through this challenging desert. They conducted a [systematic review and network meta-analysis] to compare [anti-CGRP monoclonal antibodies] and [gepants] and found that [there are no clear differences in tolerability and safety between the two classes of drugs]. This is like finding two equally promising oases in the desert, each offering a safe haven from migraine attacks.

A New Era of Migraine Treatment: Choosing the Right Path for Personalized Care

The research shows that both [anti-CGRP monoclonal antibodies] and [gepants] offer [comparable safety and tolerability] for [migraine prevention]. This provides patients with [greater flexibility] in choosing the treatment that best suits their individual needs and preferences. It's like discovering two well-maintained caravan routes through the desert, each offering a safe and comfortable journey.

Navigating the Desert of Migraine: Seeking Expert Medical Advice for Personalized Treatment

If you are struggling with [migraine], it's important to [consult with your doctor] to discuss the best treatment options for you. Remember, the desert of [migraine] can be navigated more effectively with the right support and personalized care.

Dr. Camel's Conclusion

This research provides a comprehensive comparison of [CGRP pathway treatments] for [migraine prevention], offering valuable insights for both patients and medical professionals. It's a reminder that the desert of [migraine treatment] is a complex one, but with the right knowledge and care, patients can find the path that leads to a more comfortable and fulfilling life.

Date :
  1. Date Completed 2023-02-16
  2. Date Revised 2023-02-16
Further Info :

Pubmed ID

36786548

DOI: Digital Object Identifier

10.1177/03331024231152169

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Article Analysis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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