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Efficacy and safety of adjunctive therapy with fingolimod in patients with schizophrenia: A randomized, double-blind, placebo-controlled clinical trial.
Author: AkhondzadehShahin, AmanollahiMobina, ArdakaniMohammad-Reza Khodaei, BastiFatemeh A, JameieMelika, KarbalaeeMonire, MokhtariSaba, MoradiKamyar, ParsaeiMohammadamin, TaghaviZanjaniFateme
Original Abstract of the Article :
Studies have suggested that fingolimod, a sphingosine-1-phosphate receptor modulator, exerts neuroprotective and anti-inflammatory effects. Although fingolimod is approved for the treatment of relapsing-remitting multiple sclerosis, limited studies have investigated its effects in patients with schi...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.schres.2023.02.020
データ提供:米国国立医学図書館(NLM)
Fingolimod as an Adjunctive Therapy for Schizophrenia
Schizophrenia is a severe mental illness that affects millions of people worldwide. This research investigates the potential of fingolimod, a drug typically used for multiple sclerosis, as an adjunctive therapy for schizophrenia. The study explores the efficacy and safety of fingolimod in combination with risperidone, a commonly prescribed antipsychotic, in treating schizophrenia. The authors aim to determine if fingolimod can enhance the effectiveness of traditional antipsychotic medications.
Fingolimod's Potential in Schizophrenia Treatment
The study suggests that fingolimod may offer a potential benefit for patients with schizophrenia. While fingolimod is not a primary treatment for schizophrenia, it may be used as an adjunctive therapy to augment the effects of conventional antipsychotics. The study's findings require further investigation, but they indicate that fingolimod, known for its neuroprotective and anti-inflammatory properties, could potentially play a role in improving treatment outcomes for schizophrenia.
Neuroprotective and Anti-inflammatory Effects of Fingolimod
This research highlights the potential of repurposing existing medications to address different medical conditions. The study's findings suggest that fingolimod, a drug approved for multiple sclerosis, may hold promise as an adjunctive treatment for schizophrenia. By leveraging its neuroprotective and anti-inflammatory properties, fingolimod could potentially enhance the effectiveness of conventional antipsychotic medications and improve the well-being of patients with schizophrenia.
Dr.Camel's Conclusion
Just like a camel can adapt to the harsh desert environment, fingolimod may be able to adapt its therapeutic properties to help those struggling with schizophrenia. This research represents a promising step in exploring new and innovative treatment approaches for this challenging condition. Further research is needed to fully understand the potential benefits and risks of fingolimod in the context of schizophrenia.
Date :
- Date Completed 2023-04-18
- Date Revised 2023-04-21
Further Info :
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